Sökning: "Alkaloids"

Visar resultat 26 - 30 av 36 avhandlingar innehållade ordet Alkaloids.

  1. 26. Mistletoes and Thionins : as Selection Models in Natural Products Drug Discovery

    Författare :Sonny Larsson; Anders Backlund; Lars Bohlin; Peter J. Houghton; Uppsala universitet; []
    Nyckelord :Pharmacognosy; drug discovery; mistletoe; phylogeny; cytotoxic peptides; Santalales; Farmakognosi;

    Sammanfattning : The process of drug discovery from natural products starts with the selection of study object. In this project recent knowledge and methods are incorporated to investigate the process of such selection for pharmacognostic investigations. LÄS MER

  3. 27. Heterogeneity of leukemic cells with regard to daunorubicin accumulation and efflux : potential role in drug resistance

    Författare :Eva Knaust; Linköpings universitet; []
    Nyckelord :Drug resi stance. acute myeloid leukemia; flow cytometry; gene expression; transport kinetics; apoptosis; MEDICINE; MEDICIN;

    Sammanfattning : Cellular resistance to chemotherapy is a major cause of treatment failure in acute myelocytic leukemia (AML) and other malignancies. Drug resistance is multifactorial; the most studied mechanism being multidrug resistance (MDR), mediated by the P-glycoprotein (PPG), a transmembrane transport protein with a pump function, encoded by the mdr 1 gene. LÄS MER

  4. 28. Effect of wounding and light exposure on sterol, glycoalkaloid, and calystegine levels in potato plants (Solanum tuberosum L. group Tuberosum)

    Författare :Usman Arif; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Steroidal glycoalkaloids (SGA) are neurotoxic substances that are present in some members of the Solanaceae family, including crop species like potato (Solanum tuberosum L.) and tomato. LÄS MER

  5. 29. Endophytic fungi in meadow fescue and other forage grasses

    Författare :Anja Bylin; Sveriges lantbruksuniversitet; Sveriges lantbruksuniversitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES;

    Sammanfattning : Many cool-season forage grasses associate with an endophytic fungus of the genus Epichloë. In Sweden one of the most important forage grasses is meadow fescue (Festuca pratensis Huds.), which is known to associate with Epichloë uncinata, previously named Neotyphodium uncinatum. LÄS MER

  7. 30. Analysis of sterol metabolism in the pathogenic oomycetes Saprolegnia parasitica and Phytophthora infestans

    Författare :Paul Dahlin; Vincent Bulone; Lisbeth Jonsson; Katharina Pawlowski; Lauren Mckee; Sophia Ekengren; Folke Sitbon; Steven Kelly; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Plant Physiology; växtfysiologi;

    Sammanfattning : The primary objective of this thesis was to investigate the sterol metabolism of two pathogenic oomycetes, specifically the processes of sterol synthesis and sterol acquisition in the fish pathogen Saprolegnia parasitica (Saprolegniales) and the plant pathogen Phytophthora infestans (Peronosporales). Furthermore, the effects of steroidal glycoalkaloids from Solanaceous plants, on P. LÄS MER