Sökning: "åstrand"

Visar resultat 16 - 20 av 44 avhandlingar innehållade ordet åstrand.

  1. 16. Engineering strategies for ABD-derived affinity proteins for therapeutic and diagnostic applications

    Författare :Mikael Åstrand; Sophia Hober; John Löfblom; Larry Gold; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABD; ADAPT; Protein G; ERBB2; ERBB3; Directed evolution; phage display; staphylococcal display; bispecific; Bioteknologi; Biotechnology;

    Sammanfattning : Small stable protein domains are attractive scaffolds for engineering affinity proteins due to their high tolerance to mutagenesis without loosing structural integrity. The albuminbinding domain is a 5 kDa three-helix bundle derived from the bacterial receptor Protein G with low-nanomolar affinity to albumin. LÄS MER

  3. 17. Normalization and Differential Gene Expression Analysis of Microarray Data

    Författare :Magnus Åstrand; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : DNA microarray technologies have the capability of simultaneously measuring the abundance of thousands of mRNA-sequences. Analysis of microarray data involves many different steps such as image analysis, background correction, and normalization, but also more classical statistical analysis such as testing for significant differences between groups of arrays. LÄS MER

  4. 18. On bootstrapping survival data

    Författare :Magnus Åstrand; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Bootstrap; KAplan-Meier; survival; semiiarametric; exact; dependent; KAplan-Meier;

    Sammanfattning : .... LÄS MER

  5. 19. Women's knowledge, attitudes, and management of the menopausal transition

    Författare :Lotta Lindh-Åstrand; Mats Hammar; Karin Kjellgren; Aila Collins; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Menopause; hormone therapy; knowledge; attitudes; conceptions; management treatment; climacteric symptoms; hot flushes; Obstetrics and women s diseases; Obstetrik och kvinnosjukdomar;

    Sammanfattning : Introduction: Hormone therapy (HT) has been considered as a safe treatment for menopausal symptoms. Use of HT increased dramatically in the 1980s and 1990s. Results from large randomized clinical trials (RCT) could, around the turn of the century, however not find evidence for long-term benefits with HT. LÄS MER

  7. 20. A Tactile Resonance Sensor System for Detection of Prostate Cancer ex vivo : Design and Evaluation on Tissue Models and Human Prostate

    Författare :Anders P Åstrand; Britt M Andersson; Ville Jalkanen; Olof A Lindahl; E. Göran Salerud; Umeå universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Electronics; elektronik;

    Sammanfattning : Background The most common form of cancer among males in Europe and the USA is prostate cancer, PCa. Surgical removal of the prostate is the most common form of curative treatment. LÄS MER