Sökning: "Mikael Åstrand"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden Mikael Åstrand.

1. 1. Engineering strategies for ABD-derived affinity proteins for therapeutic and diagnostic applications

   Författare :Mikael Åstrand; Sophia Hober; John Löfblom; Larry Gold; KTH; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ABD; ADAPT; Protein G; ERBB2; ERBB3; Directed evolution; phage display; staphylococcal display; bispecific; Bioteknologi; Biotechnology;

   Sammanfattning : Small stable protein domains are attractive scaffolds for engineering affinity proteins due to their high tolerance to mutagenesis without loosing structural integrity. The albuminbinding domain is a 5 kDa three-helix bundle derived from the bacterial receptor Protein G with low-nanomolar affinity to albumin. LÄS MER

3. 2. Short-term Underground Mine Scheduling : Constraint Programming in an Industrial Application

   Författare :Max Åstrand; Mikael Johansson; Christian Schulte; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; scheduling; mining; mine; underground; constraint programming; cp; large neighborhood search; lns; Electrical Engineering; Elektro- och systemteknik;

   Sammanfattning : The operational performance of an underground mine depends critically on how the production is scheduled. Increasingly advanced methods are used to create optimized long-term plans, and simultaneously the actual excavation is getting more and more automated. LÄS MER

4. 3. Short-term Underground Mine Scheduling : An Industrial Application of Constraint Programming

   Författare :Max Åstrand; Mikael Johansson; Mats Carlsson; KTH; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; scheduling; mining; underground mines; constraint programming; large neighborhood search; korttidsplanering; gruvdrift; underjordsgruvor; villkorsprogrammering; Electrical Engineering; Elektro- och systemteknik;

   Sammanfattning : The mining industry is facing a surge in automation in the pursuit of safe and profitable operations. As the excavation process is increasingly automated, today's mining companies seek to optimize the coordination of the now automated mining activities. LÄS MER

5. 4. När PBS kom till byn : Berättelser om erfarenheter av ProblemBaserad Skolutveckling

   Författare :Annika Åstrand; Hans-Åke Scherp; Héctor Pérez Prieto; Mikael Alexandersson; Karlstads universitet; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES; school development; education politics; policy; discourse; narrative; organization studies; skolutveckling; utbildningspolitik; policy; diskurs; berättelser; organisationsforskning; Education; Pedagogik; Education; Pedagogik;

   Sammanfattning : This thesis presents a study on different school actors’ narratives about how they have experienced a participation in a school development collaboration called PBS, problem based school development. A school development and research project based at Karlstad University. LÄS MER

7. 5. Protective Tribofilms on Combustion Engine Valves

   Författare :Robin Elo; Staffan Jacobson; Mikael Åstrand; Uppsala universitet; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Internal combustion engine; valve; sealing surface; tribofilm; oil residue; test rig; Teknisk fysik med inriktning mot tribomaterial; Engineering Science with specialization in Tribo Materials;

   Sammanfattning : Inside the complex machinery of modern heavy-duty engines, the sealing surfaces of the valve and valve seat insert have to endure. Right next to the combustion, temperatures are high and high pressure deforms the components, causing a small relative motion in the interface. LÄS MER