Sökning: "counter regulation"

Visar resultat 1 - 5 av 29 avhandlingar innehållade orden counter regulation.

1. 1. Glucagon Counter-Regulation to Hypoglycemia During Incretin-Based Therapy

   Författare :Johan Farngren; Lund Medicin; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Incretin; DPP-4; GLP-1; Glucagon; Hypoglycemia; Diabetes;

   Sammanfattning : Incretin-based therapy is associated with low risk of hypoglycemia in type 2 diabetes mellitus (T2DM) possibly due to its glucose-dependency in stimulating insulin secretion and a sustained glucagon response during hypoglycemia. This is of special relevance when it is combined with insulin or given to elderly patients since both insulin therapy and high age are associated with impaired glucagon counter-regulation. LÄS MER

3. 2. On the Impact of Bariatric Surgery on Glucose Homeostasis

   Författare :Niclas Abrahamsson; Britt Eden Engström; Jan Eriksson; Magnus Sundbom; Neil Gerard Docherty; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hypoglycaemia; Gastric Bypass surgery; Biliopancreatic diversion with duodenal switch DS ; NT-ProBNP; Continuous glucose measuring system CGMS ; GLP-1-analog; glucose variability; MAGE; CONGA; counter regulation; incretin; Heart Rate Variability; Endocrinology and Diabetology; Endokrinologi och Diabetologi;

   Sammanfattning : Obesity has grown to epidemic proportions, and in lack of efficient life-style and medical treatments, the bariatric surgeries are performed in rising numbers. The most common surgery is the Gastric Bypass (GBP) surgery, with the Biliopancreatic diversion with duodenal switch (DS) as an option for the most extreme cases with a BMI>50 kg/m2. LÄS MER

4. 3. Insulin-antagonistic neurohormonal pathways in the development of insulin resistance and type 2 diabetes

   Författare :Martin Lundqvist; Jan W Eriksson; Niclas Abrahamsson; André van Beek; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucagon; cortisol; ACTH; growth hormone; counter-regulation; clamp; hypoglycemia; hyperglycemia; obesity; type 2 diabetes; inflammation;

   Sammanfattning : According to the current paradigm, the development of type 2 diabetes is driven by insulin resistance and the gradual failure of beta cells to compensate for this by secreting adequate amounts of insulin. Obesity is an important risk factor for type 2 diabetes and is considered to influence disease development primarily by induction of insulin resistance, via mechanisms that have not been fully elucidated. LÄS MER

5. 4. Competition, regulation and integration in international financial markets

   Författare :Jens Nystedt; Handelshögskolan i Stockholm; []
   Nyckelord :SAMHÄLLSVETENSKAP; SOCIAL SCIENCES;

   Sammanfattning : Chapter I - Derivative Market Competition: OTC Markets Versus Organized Derivative Exchanges Recent regulatory initiatives in the United States have again raised the issue of a ''level regulatory and supervisory playing field'' and the degree of competition globally between over-the-counter (OTC) derivatives and organized derivative exchange (ODE) markets. This chapter models some important aspects of how an ODE market interrelates with the OTC markets. LÄS MER

7. 5. Regulation of assembly and cell surface dynamics of caveolae

   Författare :Jagan Mohan; Richard Lundmark; Oleg Shupliakov; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; medicinsk biokemi; Medical Biochemistry;

   Sammanfattning : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. LÄS MER