Sökning: "hypoglycemia"

Visar resultat 1 - 5 av 49 avhandlingar innehållade ordet hypoglycemia.

  1. 1. Mechanisms of Mitochondria-Induced Brain Damage Following Ischemia and Hypoglycemia

    Författare :Michel Ferrand-Drake; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cyclosporin A; neuronal death; calpain; caspase; mitochondrial permeability transition; necrosis; apoptosis; cerebral ischemia; hypoglycemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Mechanisms of Mitochondria-Induced Brain Damage Following Ischemia and Hypoglycemia Following prolonged disruption of blood flow to the central nervous system (CNS), or energy deprivation by other means, such as hypoglycemia, some cells will inevitably degenerate. It has been, and still is, the subject of considerable debate and intense research on brain ischemia, as to the mode of cell death, i. LÄS MER

  3. 2. Insulin-antagonistic neurohormonal pathways in the development of insulin resistance and type 2 diabetes

    Författare :Martin Lundqvist; Jan W Eriksson; Niclas Abrahamsson; André van Beek; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; glucagon; cortisol; ACTH; growth hormone; counter-regulation; clamp; hypoglycemia; hyperglycemia; obesity; type 2 diabetes; inflammation;

    Sammanfattning : According to the current paradigm, the development of type 2 diabetes is driven by insulin resistance and the gradual failure of beta cells to compensate for this by secreting adequate amounts of insulin. Obesity is an important risk factor for type 2 diabetes and is considered to influence disease development primarily by induction of insulin resistance, via mechanisms that have not been fully elucidated. LÄS MER

  4. 3. Roux-en-Y gastric bypass as treatment of morbid obesity

    Författare :Anna Laurenius; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Roux-en-Y gastric bypass; dietary energy density; food choice; meal size; eating rate; meal pattern; eating behavior; dumping syndrome; construct validity; hypoglycemia;

    Sammanfattning : Background and aims: Roux-en-Y gastric bypass (RYGB) is now a common treatment for obesity with well-documented effects on long-term weight reduction, health-related quality of life, obesity-related morbidity and mortality. There is a need for a better understanding of changes in dietary intake and meal-related symptoms after RYGB. LÄS MER

  5. 4. Ischemic and Hypoglycemic Brain Damage, Involvement of the Mitochondrial Permeability Transition Pore

    Författare :Hans Friberg; Lund Wallenberg Neurocentrum; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mitochondrial permeability transition pore; mitochondria; apoptosis; neuronal death; brain; ischemia; hypoglycemia; Neurology; neuropsychology; neurophysiology; Neurologi; neuropsykologi; neurofysiologi;

    Sammanfattning : Brain damage from ischemia-reperfusion and hypoglycemia are major causes of morbidity and mortality. Therapeutic strategies include hypothermia, glutamate-receptor blockade, immunosuppression and lately treatment aiming at preserving mitochondrial integrity and function. LÄS MER

  7. 5. The neuropeptides GRP and PACAP and the function of the endocrine pancreas - A study on receptor deficient mice

    Författare :Kristin Persson; Lund Medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endocrinology; secreting systems; diabetology; Endokrinologi; sekretion; hypoglycemia; glucagon; insulin; islet of Langerhans; diabetes; PACAP; neuropeptides; GRP; diabetologi;

    Sammanfattning : The parasympathetic nerves are important for the regulation of insulin secretion, in particular after meal intake. Apart from acetylcholine, several neuropeptides can be found in the parasympathetic nerves innervating the islets of Langerhans, including gastrin-releasing peptide (GRP) and pituitary adenylate cyclase activating polypeptide (PACAP). LÄS MER