Sökning: "medicinsk biokemi"

Visar resultat 1 - 5 av 133 avhandlingar innehållade orden medicinsk biokemi.

1. 1. Studies of Functional Interactions within Yeast Mediator and a Proposed Novel Mechanism for Regulation of Gene Expression

   Detta är en avhandling från Umeå : Medicinsk biokemi och biofysik

   Författare :Magnus Hallberg; Umeå universitet.; [2004]
   Nyckelord :MEDICIN; MEDICINE; Biochemistry; Mediator; Transcriptional regulation; Srb10; Cdk8; Med2; Srb7; Med21; RNA pol II; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : The yeast Mediator complex is required for transcriptional regulation both in vivo and in vitro and the identification of similar complexes from metazoans indicates that its function is conserved through evolution. Mediator subunit composition and structure is well characterized both by biochemical, genetic and biophysical methods. LÄS MER

3. 2. Matrix degrading proteases in the ovary : expression and function

   Detta är en avhandling från Umeå : Medicinsk biokemi och biofysik

   Författare :Patrik Wahlberg; Umeå universitet.; [2004]
   Nyckelord :MEDICIN; MEDICINE; Biochemistry; ovary; ovulation; corpus luteum; plasminogen; PA; MMP; rat; mouse; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : Extracellular matrix degrading proteases from the plasminogen (plg) activator (PA) and the matrix metalloproteinase (MMP) systems have been implicated as important mediators of ovulation and corpus luteum (CL) formation and regression. The aim of this thesis was to investigate the expression and regulation of PAs and MMPs in the ovary and to examine their functional roles for CL formation and function. LÄS MER

4. 3. Studies on the transmembrane signaling of β1 integrins

   Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

   Författare :Annika Armulik; Uppsala universitet.; [2000]
   Nyckelord :MEDICIN; MEDICINE; Biochemistry; Integrin β1; signaling; transmembrane domain; CAS; focal adhesion kinase; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : Integrins are heterodimeric cell surface receptors, composed of an α and a β subunit, mainly binding for extracellular matrix proteins. lntegrin subunit β1 can combine with at least 12 a subunits and thus form the biggest subfamily within the integrin family. LÄS MER

5. 4. The expression and regulation of hyaluronan synthases and their role in glycosaminoglycan synthesis

   Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

   Författare :Jonas Brinck; Uppsala universitet.; [2000]
   Nyckelord :MEDICIN; MEDICINE; Biochemistry; hyaluronan; glycosaminoglycans; CD44; growth factors; UDP-glucose dehydrogenase; Biokemi; Medical Biochemistry; medicinsk biokemi;

   Sammanfattning : The glycosaminoglycan hyaluronan is an essential component of the extracellular matrix in all higher organisms, affecting cellular processes such as migration, proliferation and differentiation. Hyaluronan is synthesized by a plasma membrane bound hyaluronan synthase (HAS) which exists in three genetic isoforms. LÄS MER

7. 5. Regulation of hyaluronan biosynthesis : Expression in vitro and importance for tumor progression

   Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

   Författare :Annica Jacobson; Uppsala universitet.; [2002]
   Nyckelord :MEDICIN; MEDICINE; Biochemistry; Biokemi; Biochemistry; biokemi;

   Sammanfattning : Hyaluronan, a component of the extracellular matrix, is synthesized by either of three hyaluronan-synthesizing enzymes termed Has1, Has2 and Has3. The expression level of each Has gene varies between cell types of mesenchymal origin and is differentially regulated in response to external stimuli. LÄS MER