Sökning: "Richard Lundmark"
Visar resultat 1 - 5 av 9 avhandlingar innehållade orden Richard Lundmark.
1. Sorting nexin 9 in clathrin-mediated endocytosis
Sammanfattning : Clathrin-mediated endocytosis is a process by which cells can internalise diverse molecules such as nutrients, antigens and signalling-surface receptors. The creation of clathrin-coated vesicles demands interplay between the plasma membrane lipids, cargo molecules and the proteins that build up the coat. LÄS MER
2. Regulation of GRAF1 membrane sculpting function during cell movement
Sammanfattning : All eukaryotic cells rely on endocytic events to satisfy a constant need for nutrient and fluid uptake from their surroundings. Endocytosis-dependent turnover of cell surface constituents also serves to control signal transduction and establish morphological changes in response to extracellular stimuli. LÄS MER
3. Non-canonical ATG8 conjugation in ESCRT-driven membrane remodeling processes
Sammanfattning : ATG8 family proteins have the unique ability to conjugate to membrane lipids. Initially identified as a hallmark of autophagy, ATG8 lipidation is emerging as an important regulator of a growing list of non-degradative cellular functions. LÄS MER
4. Macromolecular organization of the chikungunya virus replication organelle
Sammanfattning : The chikungunya virus is a positive-sense RNA virus responsible for the crippling chikungunya fever. It is transmitted through the bites of two species of mosquitoes: Aedes aegypti and Aedes albopictus. LÄS MER
5. Regulation of assembly and cell surface dynamics of caveolae
Sammanfattning : A typical mammalian cell plasma membrane displays a high level of plasticity counter balanced with stability. The plasma membrane show various kinds of invaginations to meet physiological demands of the cells such as nutrient uptake, receptor signaling etc. An example of one such invagination observed in many cell types is “Caveola”. LÄS MER