Sökning: "Teet Velling"

Hittade 3 avhandlingar innehållade orden Teet Velling.

  1. 1. Muscle cell integrins in vitro and in vivo : Identification and characterisation of a novel integrin, α11β1

    Författare :Teet Velling; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; integrins; α7 integrin; α11 integrin; embryonic development; muscle; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; molekylär cellbiologi; Molecular Cellbiology;

    Sammanfattning : Integrins are heterodimeric receptors composed of non-covalently associated αand β subunits which have distinct functions on different cell types. α7β1integrin is an important laminin receptor in skeletal muscle. The mRNA andprotein expression patterns of α7A and α7B splice variants during mousedevelopment were studied. LÄS MER

  3. 2. Structural and Functional Aspects of β1 Integrin Signalling

    Författare :Stina Nilsson; Staffan Johansson; Teet Velling; Maria Fällman; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; Integrin; Integrin subunit β1; Integrin activation; Threonine; Phosphorylation; Integrin signalling; FAK; PI3K; MAPK; Cell- och molekylärbiologi;

    Sammanfattning : Integrins are transmembrane glycoproteins primarily mediating interactions of cells with the extracellular matrix. Each receptor is a complex of one α- and one β-subunit with affinity for a diverse set of ligands. LÄS MER

  4. 3. Tissue Factor Biological Functions : Coagulation Activity in Microparticles and Signaling with Focus On Migration and Apoptosis

    Författare :Mikael Åberg; Agneta Siegbahn; Carl-Henrik Heldin; Teet Velling; Björn Dahlbäck; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Tissue factor; Apoptosis; Migration; Chemotaxis; Simvastatin; Platelet Derived Growth Factor; Cell Signaling; Microparticles; Prostasomes; Trombosis; Coagulation; Prostate Cancer; Breast Cancer; Caspase-3; Caspase-8; NFkappaB; PAR2; Transactivation; Monocytes; Clinical chemistry; Klinisk kemi;

    Sammanfattning : Background: Tissue factor (TF) is a 47 kDa transmembrane glycoprotein known as the main initiator of blood coagulation. TF is over-expressed on many malignant cells and apart from increasing the risk of thrombosis, the presence of TF/FVIIa also promotes the progression of cancer and metastasis by intracellular signaling. LÄS MER