Sökning: "molekylär cellbiologi"

Visar resultat 1 - 5 av 158 avhandlingar innehållade orden molekylär cellbiologi.

  1. 1. Non-protein-coding RNA : Transcription and regulation of ribosomal RNA

    Författare :Stefanie Böhm; Ann-Kristin Östlund Farrants; Brian McStay; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ribosomal RNA; non-coding RNA; ribosomal genes; rDNA gene; B-WICH; chromatin remodelling; histone modification; Cell Biology; cellbiologi;

    Sammanfattning : Cell growth and proliferation are processes in the cell that must be tightly regulated. Transcription of ribosomal RNA and ribosomal biogenesis are directly linked to cell growth and proliferation, since the ribosomal RNA encodes for the majority of transcription in a cell and ribosomal biogenesis influences directly the number of proteins that are synthesized. LÄS MER

  3. 2. Hsp70 nucleotide exchange factor Fes1 is essential for protein quality control in Saccharomyces cerevisiae

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Heat shock protein 70; molecular chaperone; ubiquitin; nucleotide exchange factor; protein quality control; Cell Biology; cellbiologi;

    Sammanfattning : .... LÄS MER

  4. 3. Regulation of Hsp70 function by nucleotide-exchange factors

    Författare :Naveen Kumar Chandappa Gowda; Claes Andréasson; Gary Jones; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Heat shock proteins Hsps ; Hsp70; Molecular chaperones; Nucleotide-exchange factors NEFs ; Protein quality control PQC ; Proteostasis; Ubiquitin-proteasome system; Cell Biology; cellbiologi;

    Sammanfattning : Protein folding is the process in which polypeptides in their non-native states attain the unique folds of their native states. Adverse environmental conditions and genetic predisposition challenge the folding process and accelerate the production of proteotoxic misfolded proteins. LÄS MER

  5. 4. The cell biology and catalytic properties of the nutrient-induced signaling endoprotease Ssy5

    Författare :António Martins; Per O. Ljungdahl; Bruno André; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nutrient sensing; signal transduction; regulated proteolysis; endoprotease; serine protease; substrate specificity; subcellular fractionation; Saccharomyces cerevisiae; Cell Biology; cellbiologi;

    Sammanfattning : Cells continuously sense and respond to changes in the presence, quality and quantity of external and internal nutrients. Specific signaling proteases have been identified based on their roles in processing or destruction of distinct sets of downstream effector proteins in response to environmental cues. LÄS MER

  7. 5. Profilins : The Control of the Microfilament and Microtubule systems

    Författare :Michaela Nejedla; Roger Karlsson; Klemens Rottner; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Profilin; Actin; Microtubules; Cell Biology; cellbiologi;

    Sammanfattning : The microtubule and actin filament systems are important for many cellular processes such as intracellular organelle trafficking, cell adhesion, migration and mitosis. The two filament systems are closely connected, operate in parallel and are essential for proper cell function. LÄS MER