Sökning: "Respiratorisk immunofarmakologi"

Hittade 5 avhandlingar innehållade orden Respiratorisk immunofarmakologi.

  1. 1. Targeting viral induced TSLP - an airway treatment opportunity

    Författare :Angelica Brandelius; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Respiratory viral infections cause exacerbations of asthma and COPD that cannot be effectively treated today. Thymic Stromal Lymphopoietin (TSLP) is an upstream epithelial cytokine linking the innate and adaptive immune system. Viral stimuli induce epithelial overexpression of TSLP in asthma and COPD. LÄS MER

  3. 2. Emerging role of RIG-I-like receptors in antiviral innate immunity in airway structural cells

    Författare :Jenny Calvén; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Respiratory viral infections, especially involving rhinovirus, are main triggers of exacerbations of asthma and COPD. These severe conditions are a great burden to both the individual and society and currently lack effective treatments. LÄS MER

  4. 3. Altered viral resistance and tolerance as pathogenic mechanisms of allergic airway inflammation

    Författare :Samuel Cerps; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; exacerbation;

    Sammanfattning : .... LÄS MER

  5. 4. Translational studies of viral-induced asthma and COPD exacerbations

    Författare :Irma Mahmutovic Persson; Respiratorisk immunofarmakologi; []
    Nyckelord :Asthma; exacerbation models; COPD; dsRNA; Th2; Virus; house dust mites HDM ; TSLP; IL-1β; IL-25; IL-33;

    Sammanfattning : .... LÄS MER

  7. 5. On causes and regulation of anti-viral defence in asthma and COPD

    Författare :Mandy Menzel; Respiratorisk immunofarmakologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; ; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress; asthma; chronic obstructive pulmonary disease; rhinovirus; exacerbation; airway epithelial cell; pattern recognition receptors; interferon; allergen; azithromycin; inflammasome; epithelial-derived cytokines; oxidative stress;

    Sammanfattning : Rhinovirus infection is a main trigger of asthma and COPD exacerbations. dsRNA, a viral replication intermediate, is sensed by pattern recognition receptors in the airway epithelium leading to down-stream induction of anti-viral interferons. LÄS MER