Sökning: "Th2"

Visar resultat 1 - 5 av 229 avhandlingar innehållade ordet Th2.

  1. 1. Antibodies during pregnancy : Aspects on complications during pregnancy and complications related to transfusion

    Författare :Miodrag Palfi; Olof Sjöberg; Linköpings universitet; []
    Nyckelord :Pregnancy; Thl; Th2; hernolytic disease of the newborn; anti-D; IgG subclasses; IgG transport; post-transfusion reactions; acute lung injury; MEDICINE; MEDICIN;

    Sammanfattning : The fetus acquires half of its genetic infonnation from the father and represents a foreign graft in pregnancy. The overall mechanisms contributing to immunologic tolerance and successful pregancy still are an enigma. Accumulating results of immunologic research, however, offer an explanation for many events in pregnancy. LÄS MER

  3. 2. Transforming Growth Factor-b, Regulatory functions on normal lymphocytes and tumor outgrowth Regulatory functions on normal lymphocytes and tumor outgrowth

    Författare :Åsa Schiött; Institutionen för immunteknologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TGF-b; monocyte; rat; costimulation; Th2; ERK; tumor; TIL; Immunology; serology; Immunologi; transplantation; T-lymphocyte; serologi;

    Sammanfattning : Transforming growth factor-beta (TGF-b) is a well-characterised growth regulatory factor, which acts on most cell types. This thesis has focused on the regulatory roles of TGF-b on normal lymphocytes. One interesting finding is that TGF-b acts both costimulatory and inhibitory on T-lymphocytes. LÄS MER

  4. 3. Mechanistic studies of the adjuvant effects of CTA1-DD and the native cholera toxin: Impact of cell targeting and tissue localization

    Författare :Johan Mattsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Vaccines; adjuvants; cholera toxin; germinal center; CTA1-DD; follicular dendritic cells; denritic cells; Th1; Th2; Th17; complement;

    Sammanfattning : Vaccines are the most effective means of preventing infectious diseases and improving global health. However, few vaccines have successfully been developed for protection at mucosal surfaces where most pathogens gain access. LÄS MER

  5. 4. Effect of thimerosal on the murine immune system : especially induction of systemic autoimmunity

    Författare :Said Havarinasab; Per Hultman; Klas Nordlind; Linköpings universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; thimerosal; ethylmercury; autoimmunity; mice; immunosuppression; Th1; Th2; Pathology; Patologi;

    Sammanfattning : The organic mercury compound ethylmercurithiosalicylate (thimerosal), an antiseptic and a preservative, has recently raised public health concern due to its presence in vaccines globally. Thimerosal dissociates in the body to thiosalicylate and ethyl mercury (EtHg), which is partly converted to inorganic mercuric mercury (Hg2+). LÄS MER

  7. 5. Genital tract CD4+ T cells for vaccination and protection against Chlamydia trachomatis

    Författare :Ellen Marks; Göteborgs universitet; []
    Nyckelord :Chlamydia; T cell differentiation; genital tract; vaccination; costimulation; Th1; Th2; Th17; Tregs;

    Sammanfattning : Vaccination strategies for protection against sexually transmitted diseases (STDs) are lacking due to an incomplete understanding of genital tract T cell responses. This thesis dissects the generation of T helper subsets, including the recently discovered Th17 subset, during genital tract infection with a common sexually transmitted pathogen, Chlamydia trachomatis, and addresses vaccine requirements for the generation of genital tract CD4+ T cell immunity. LÄS MER