Sökning: "IL-33"

Visar resultat 1 - 5 av 25 avhandlingar innehållade ordet IL-33.

  1. 1. Allergic and non-allergic asthma: Translational research in immunology

    Författare :Emma Boberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ILC2s; eosinophils; IL-33; miRNAs; proteomics;

    Sammanfattning : Asthma is a chronic heterogeneous respiratory disease affecting more than 300 million people globally. The different phenotypes, including allergic and nonallergic asthma, are driven by different underlying mechanisms illustrating the complexity of the disease. LÄS MER

  3. 2. Eosinophils, their progenitors and T helper cells in allergic airway inflammation

    Författare :You Lu; Göteborgs universitet; []
    Nyckelord :eosinophils; eosinophil progenitors; T helper cells; Th2 cells; IL-33; migration; Asthma;

    Sammanfattning : Introduction: Asthma is a heterogeneous chronic lung disease associated with pronounced inflammatory changes in the airways. Eosinophilic inflammation is the trait that is best linked to symptoms and treatment responses in allergic asthma. LÄS MER

  4. 3. Mechanisms triggering the recruitment of mast cell progenitors to the lung and regulation of mast cell degranulation

    Författare :Behdad Zarnegar; Jenny Hallgren; Madeleine Rådinger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mast cells; Mast cell progenitors; Recruitment; Lung; Virus; Influenza; Innate immunity; Poly I:C; IL-33; VAAT; SLC10A4; Degranulation;

    Sammanfattning : Mast cells stem from the bone marrow and migrate via the blood as mast cell progenitors. Upon arrival in peripheral tissues, they develop into mast cells. These rare immune cells have numerous granules that contain large amounts of pro-inflammatory mediators. LÄS MER

  5. 4. Translational studies of viral-induced asthma and COPD exacerbations

    Författare :Irma Mahmutovic Persson; Respiratorisk immunofarmakologi; []
    Nyckelord :Asthma; exacerbation models; COPD; dsRNA; Th2; Virus; house dust mites HDM ; TSLP; IL-1β; IL-25; IL-33;

    Sammanfattning : .... LÄS MER

  7. 5. Targeting the IL-33/ST2 pathway in asthma : implications for development, exacerbation and treatment

    Författare :Anna Zoltowska Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma is a term that encompasses a disease spectrum with different phenotypes that vary in severity and whose common characteristic is airflow limitation. Allergic asthma is the most common phenotype of asthma and is characterized by allergen induced inflammatory responses, airway hyperresponsiveness (AHR), and remodeling. LÄS MER