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Visar resultat 1 - 5 av 120 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Regulation of Drosophila Jun by phosphorylation and the ubiquitin system during eye development

    Författare :Anders Isaksson; Biologiska institutionen; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; eye development; ubiquitin; D-Jun; phosphorylation; cytogenetics; Genetik; cytogenetik;

    Sammanfattning : The goal of these studies has been to elucidate the biological relevance of post-translational modifications in the context of a living organism. The model system used is photoreceptor differentiation during development of the compound eye in the fruit fly Drosophila melanogaster. LÄS MER

  3. 2. Intracellular components involved in parathyroid sensing of extracellular calcium

    Författare :Isaac G. Onyango; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biochemistry; Parathyroid hormone; secretion; Src kinase; ERK; PI 3-kinase; PKC; extracellular calcium; parathyroid cell; Biokemi; Biochemistry; Biokemi; Medical and Physiological Chemistry; medicinsk och fysiologisk kemi;

    Sammanfattning : Parathyroid glands are the primary regulator of extracellular calcium ([Ca2+]e). Ca2+ plays a key role in many fundamental biological processes and is also an essential structural component of the skeleton. The parathyroid chief cells detect small changes in [Ca2+]e and respond by altering the secretion of parathyroid hormone (PTH). LÄS MER

  4. 3. Structural and Functional Aspects of β1 Integrin Signalling

    Författare :Stina Nilsson; Staffan Johansson; Teet Velling; Maria Fällman; Uppsala universitet; []
    Nyckelord :Cell and molecular biology; Integrin; Integrin subunit β1; Integrin activation; Threonine; Phosphorylation; Integrin signalling; FAK; PI3K; MAPK; Cell- och molekylärbiologi;

    Sammanfattning : Integrins are transmembrane glycoproteins primarily mediating interactions of cells with the extracellular matrix. Each receptor is a complex of one α- and one β-subunit with affinity for a diverse set of ligands. LÄS MER

  5. 4. Prostasome Modulation of Blood Cascade System and Phosphoprotein Reactions with Focus on Prostate Cancer

    Författare :Adil Abdelgadir Babiker; Kristina Nilsson Ekdahl; Michael Wilson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; ATPase; CD59; Complement; DU145; Extracellular phosphorylation; LNCaP; PC-3; Prostasomes; Prostate cancer; Protein kinases; Tissue factor; Immunologi; Immunology; Immunologi;

    Sammanfattning : Prostasomes are extracellularly occurring submicron, membrane-surrounded organelles produced by the epithelial cells of the prostate and present in semen. Their precise physiological role is not known, although some of their properties assign them to important physiological and patho-physiological functions. LÄS MER

  7. 5. Biosynthesis of decorin and glypican glycosaminoglycan chains

    Författare :Mats Jönsson; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Metabolism; Biochemistry; phosphorylation; biosynthesis; glycosaminoglycan; decorin; glypican; Biokemi; metabolism;

    Sammanfattning : Proteoglycans consist of core proteins substituted with glycosaminoglycan chains. The galactosaminoglycans (GlcUA/IdoUA-GalNAc) and the glucosaminoglycans (GlcUA/IdoUA-GlcNAc) are both initiated on the same tetrasaccharide linkage region GlcUA-Gal-Gal-Xyl-protein. LÄS MER