Sökning: "LNCaP"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet LNCaP.

  1. 1. Prostasome Modulation of Blood Cascade System and Phosphoprotein Reactions with Focus on Prostate Cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Adil Abdelgadir Babiker; Uppsala universitet.; [2005]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immunology; ATPase; CD59; Complement; DU145; Extracellular phosphorylation; LNCaP; PC-3; Prostasomes; Prostate cancer; Protein kinases; Tissue factor; Immunologi; MEDICINE Microbiology; immunology; infectious diseases Immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi;

    Sammanfattning : Prostasomes are extracellularly occurring submicron, membrane-surrounded organelles produced by the epithelial cells of the prostate and present in semen. Their precise physiological role is not known, although some of their properties assign them to important physiological and patho-physiological functions. LÄS MER

  2. 2. Phytoestrogens and prostate cancer experimental, clinical, and epidemiological studies

    Detta är en avhandling från Umeå : Kirurgisk och perioperativ vetenskap

    Författare :Annika Bylund; Umeå universitet.; [2007]
    Nyckelord :prostatic neoplasm; phytoestrogens; lignans; enterolactone; rye; 7-hydroxymataireorcinol; nude mice; TRAMP mice; nested case control study; LNCaP; Oncology; onkologi;

    Sammanfattning : Dietary factors may affect development and progression of prostate cancer. Experimental and epidemiological studies have suggested an effect of phytoestrogens on prostate cancer. Lignans are the predominant phytoestrogen in a Western diet. LÄS MER

  3. 3. Regulation of Vitamin D 25-hydroxylases Effects of Vitamin D Metabolites and Pharmaceutical Compounds on the Bioactivation of Vitamin D

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Maria Ellfolk; Uppsala universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CYP2D25; vitamin D 25-hydroxylase; transcriptional regulation; vitamin D; CYP2R1; CYP2J2; CYP27A1; phenobarbital; efavirenz; fibroblast; LNCaP; PHARMACY Pharmaceutical biochemistry; FARMACI Farmaceutisk biokemi;

    Sammanfattning : A 700bp portion of the promoter of CYP2D25, the porcine microsomal vitamin D 25-hydroxylase was isolated and sequenced. The computer analysis of the sequence revealed the existence of a putative VDRE at 220 bp upstream of the transcription start site. LÄS MER

  4. 4. Androgen-Independent Prostate Cancer - studies on angiogenesis and ADAMTS1

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Helene Gustavsson; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; Androgen-independent; Castration resistant; Hormone refractory; Angiogenesis; Microvessel density; ADAMTS1; LNCaP; VEGF; TSP1;

    Sammanfattning : Androgen deprivation therapy (ADT) is the standard treatment for advanced prostate cancer since prostate tumors initially are dependent on androgens for growth. However, most tumors will eventually relapse and grow in a highly aggressive and androgen-independent (AI) manner. LÄS MER

  5. 5. Radioimmunoimaging and Radioimmunotherapy of Prostate Cancer Preclinical evaluation of kallikrein related peptidase 2 targeting

    Detta är en avhandling från Department of Medical Radiation Physics, Clinical Sciences, Lund, Lund University

    Författare :Oskar Vilhelmsson Timmermand; Lunds universitet.; Lund University.; [2014]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; radioimmunotherapy; Radioimmunoimaging; antibody; 11B6; indium-111; lutetium-177; kallikrein related peptidase 2; hK2; PSA; prostate cancer; SPECT; KLK2; cherenkov luminescence imaging; CLI;

    Sammanfattning : Prostate cancer is one of the major causes of cancer related deaths in men in Europe and the United States. In this doctoral thesis, radioimmunoimaging and -therapy of prostate cancer was investigated pre-clinically by targeting the human kallikrein-related peptidase 2 (hK2) with radiolabelled monoclonal antibodies. LÄS MER