Sökning: "vascular dysfunction"

Visar resultat 31 - 35 av 186 avhandlingar innehållade orden vascular dysfunction.

  1. 31. Studies on vascular remodeling in acute coronary artery disease

    Författare :Fei Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Atherosclerosis; unstable angina; matrix metalloproteinase; apoptosis; angiogenesis; remodeling;

    Sammanfattning : Atherosclerosis is an arterial disease, characterized by endothelial dysfunction, vascular inflammation, and lipid accumulation in the vessel wall. Unstable coronary syndroms may be initiated by rupture of the atherosclerotic plaque, which may be caused by activation of matrix metalloproteinases (MMPs), apoptosis and angiogenesis. LÄS MER

  3. 32. Endothelial function and dysfunction in coronary artery bypass grafting

    Författare :Ulf Lockowandt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :CABG; Endothelin; Endothelin-blockers; endothelium; lactate; off-pump CABG; prostacyclin; radial artery; unstable angina pectoris;

    Sammanfattning : The integrity of the endothelium is of importance for short- and long-term results following coronary artery bypass grafting (CABG). In this thesis different factors of the endothelial role in the regulation of vascular tone in relation to various current aspects of CABG have been investigated. LÄS MER

  4. 33. Cellular and molecular roles for CDC42 in angiogenesis

    Författare :Marco Castro; Christer Betsholtz; Bàrbara Laviña; Rui Benedito; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CDC42; angiogenesis; endothelial cell; vascular malformation; Biology with specialization in Molecular Cell Biology; Biologi med inriktning mot molekylär cellbiologi;

    Sammanfattning : Angiogenesis is the physiological process by which new blood vessels grow and critically depends on the interplay between the major vascular units: endothelial cells, pericytes and smooth muscle cells. Dysfunction and mispatterning of blood vessels are associated with the progression of many vascular complications, and therefore, understanding the causes of vascular dysmorphia is a central question in vascular biology. LÄS MER

  5. 34. Novel cardiovascular risk factors in childhood

    Författare :Michal Odermarsky; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; environmental tobacco smoke; vascular function; infection; type 1 diabetes; HLA;

    Sammanfattning : Individuals with type 1 diabetes (T1D) have a 2 to 3-fold increased risk for cardiovascular disease compared to non-diabetic subjects. Exposure to a broad panel of risk factors in childhood may cause vascular damage with potentially long-term consequences for cardiovascular morbidity. LÄS MER

  7. 35. Cerebral white matter changes in patients with cognitive impairment - clinical and pathophysiological aspects

    Författare :Michael Jonsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; white matter changes; vascular factors; cognitive impairment; neuropsychiatric symptoms; cerebrospinal fluid biomarkers; demyelination; axonal degeneration;

    Sammanfattning : Cerebral white matter changes (WMC), detected with computed tomography (CT) or magnetic resonance imaging (MRI), represent a common condition in elderly people. However, the prognostic, symptomatological and biochemical constituents of WMC are only partially known. LÄS MER