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Visar resultat 1 - 5 av 6 avhandlingar som matchar ovanstående sökkriterier.

1. 1. The Palaeopathology of Kirchberg : Evidence of Deficiency, Inflammatory and Tumorous Disease in a Medieval Rural Population in Hessia, Germany

   Författare :Nikolaos Roumelis; Jan Storå; Michael Schultz; Pia Bennike; Stockholms universitet; []
   Nyckelord :HUMANIORA; HUMANITIES; Kirchberg; rural population; Middle Ages; palaeohistopathology; palaeopathology; microscopy; diagnosis; health; inflammatory disease; tumorous disease; micrometastases; deficiency disease; environment.; Archaeology; Arkeologi; osteoarkeologi; Osteoarchaeology;

   Sammanfattning : This study investigates the interaction of disease processes, disease and environment, female and male health as well as health and ageing in a medieval rural village population. For this purpose multiple skeletal indicators of health have been studied, including deficiency, inflammatory, infectious and tumorous disease. LÄS MER

3. 2. Molecular aspects of parathyroid tumorigenesis : with focus on parafibromin and the Wnt pathway

   Författare :Christofer Juhlin; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Primary hyperparathyroidism (PHPT) denotes the tumorous enlargement of one or several parathyroid glands and constitutes a common disorder, particularly pronounced among postmenopausal women. PHPT patients display hypercalcemia as a consequence of parathyroid hormone hypersecretion, and the symptomatology is habitually based on this metabolic aberrancy. LÄS MER

4. 3. Cholangiocarcinoma in primary sclerosing cholangitis

   Författare :Annika Bergquist; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Primary sclerosing cholangitis; pancreatic carcinoma; cholangiocarcinoma; ulcerative colitis; biliary dysplasia; apoptosis; Ki-67; p53; bcl-2.;

   Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10-20% of patients with PSC. LÄS MER

5. 4. Experimental and clinical studies on liver regeneration and hepatocellular carcinoma : roles of redox proteins, iron homeostasis and multikinase inhibition

   Författare :Annelie Mollbrink; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Compensatory liver regeneration is triggered by chronic liver injury or surgery and is crucial to maintain tissue homeostasis. The underlying mechanisms which include a whole battery of complex signaling events have been thoroughly studied for decades. LÄS MER

7. 5. Brain Tumor Imaging and Treatment Effects. Imaging findings and cognitive function in glioblastoma patients

   Författare :Anna Rydelius; Lund Neurologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Glioblastoma; Imaging finding; Quantitative volumetry; Cognitive function; Diffusion tensor imaging DTI ; Treatment effect; Radiotherapy; VMAT; Parametric response maps PRM ; Treatment responce prediction;

   Sammanfattning : AbstractBackground: Glioblastoma is the most common malignant brain tumor. Operation with maximal resection, if feasible, otherwise biopsy followed by radiotherapy and chemotherapy with temozolomide is standard therapy. The prognosis remains poor, with median overall survival being 15 months despite therapy. LÄS MER