Sökning: "biliary dysplasia"

Hittade 3 avhandlingar innehållade orden biliary dysplasia.

  1. 1. Cholangiocarcinoma in primary sclerosing cholangitis

    Författare :Annika Bergquist; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Primary sclerosing cholangitis; pancreatic carcinoma; cholangiocarcinoma; ulcerative colitis; biliary dysplasia; apoptosis; Ki-67; p53; bcl-2.;

    Sammanfattning : Primary sclerosing cholangitis (PSC) is a chronic cholestatic liver disease of unknown causes closely associated with ulcerative colitis. PSC is a progressive disease leading to liver failure and need for liver transplantation. Cholangiocarcinoma (CC) occurs in 10-20% of patients with PSC. LÄS MER

  3. 2. Endoscopic methods for detecting malignancy in patients with ulcerative colitis and primary sclerosing cholangitis

    Författare :Bo Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Ulcerative colitis; primary sclerosing cholangitis; cholangiocarcinoma; colorectal cancer; dysplasia; brush cytology; Endoscopic Retrograde Cholangiopancreatography ERCP .;

    Sammanfattning : Ulcerative colitis (UC) is a chronic ulcerative inflammatory bowel disease affecting the mucosa of the large intestine. UC patients have an increased risk for the development of colorectal cancer mainly associated with long duration and extensive involvement of the colitis. LÄS MER

  4. 3. Gallbladder and pancreatic disease in patients with primary sclerosing cholangitis

    Författare :Karouk Said; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cholecystitis; gallbladder; ejection fraction; magnetic resonance imaging; pancreatic duct; chronic pancreatitis; thioredoxin; Immunohistochemical staining;

    Sammanfattning : The aims of this study were to assess the occurrence of gallbladder abnormalities and dysfunction, to evaluate clinically useful biomarkers for premalignancy and malignancy in gallbladder epithelium and to assess presence of pancreatic duct changes and early pancreatic abnormalities in patients with primary sclerosing cholangitis (PSC). In paper I and III we investigated presence of gallbladder abnormalities in 286 patients with PSC treated at Karolinska University Hospital, Huddinge, between 1970 and 2005. LÄS MER