Sökning: "transkriptomik"

Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet transkriptomik.

  1. 1. Mapping Transcriptomes in Tissues

    Författare :Ludvig Larsson; Joakim Lundeberg; Stefania Giacomello; Naveed Ishaque; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; spatially resolved transcriptomics; spatial transcriptomics; transcriptomics; data analysis; rumsligt upplöst transkriptomik; rumslig transkriptomik; transkriptomik; dataanalys; Biotechnology; Bioteknologi;

    Sammanfattning : Over the past few decades, the advent of pioneering biotechnological methods has allowed scientists to analyze the molecular components of multicellular organisms with remarkable precision. The field of transcriptomics has witnessed a rapid development of technologies for gene expression profiling of biological samples. LÄS MER

  3. 2. Spatial mapping of bacteria and transcriptomes

    Författare :Britta Lötstedt; Joakim Lundeberg; Anders F. Andersson; Petri Auvinen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; spatial transcriptomics; 16S sequencing; antibody-based measurements; spatiell transkriptomik; 16S-sekvensering; antikroppsbaserade mätningar; Biotechnology; Bioteknologi;

    Sammanfattning : Novel insights into biological functions and mechanisms, cell networks and evolutionary relationships are gained through development of sequencing technologies and sequencing based applications. Massively parallel sequencing has enabled analysis of big data at gene and protein expression levels, but has also characterized bacterial communities. LÄS MER

  4. 3. Exploring the transcriptional space

    Författare :Joseph Bergenstråhle; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :Transcriptomics Spatial; Bioteknologi; Biotechnology;

    Sammanfattning : Transcriptomics promises biological insight into gene regulation, cell diversity, and mechanistic understanding of dysfunction. Driven by technological advancements in sequencing technologies, the field has witnessed an exponential growth in data output. Not only has the amount of raw data increased tremendously but it’s granularity as well. LÄS MER

  5. 4. Development and application of spatial transcriptomics methods

    Författare :Zaneta Andrusivova; Joakim Lundeberg; Jay W. Shin; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; RNA; Spatial Transcriptomics; RNA sequencing; Biotechnology; Bioteknologi;

    Sammanfattning : Transcriptomics is one of the pivotal fields in molecular biology, enabling comprehensive analysis of gene expression patterns. Recent advancements in the biotechnology field have transformed the transcriptomics research, providing insights into the complexity of cellular processes in a greater detail. LÄS MER

  7. 5. Mammalian protein expression and characterization tools for next generation biologics

    Författare :Niklas Thalén; Johan Rockberg; Kerstin Otte; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; CHO; Cell line engineering; Protein engineering; GFP; Cell display; Biotechnology; Bioteknologi;

    Sammanfattning : Protein therapeutics are increasingly important for modern medicine. Novel recombinant proteins developed today can bind towards their target with high specificity and with low adverse effect. This has enabled the treatment of diseases that for a few years ago were deemed uncurable. LÄS MER