Sökning: "thyroid dysfunction"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden thyroid dysfunction.

  1. 1. Affective disorders and their treatments : implications for thyroid function

    Författare :Ingrid Lieber; Ursula Werneke; Michael Ott; Mats Eliasson; John McGrath; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Bipolar disorder; affective disorder; lithium; thyroid dysfunction; hyperthyroidism; hypothyroidism; Delphi-consensus; psykiatri; Psychiatry;

    Sammanfattning : BackgroundThe relationship between affective disorders, mood-stabilisers and thyroid dysfunction is complex and poorly understood. Symptoms of thyroid dysfunction can overlap with symptoms of affective disorder, destabilise mood, and impact physical health. LÄS MER

  3. 2. Regulation of apoptosis in the thyroid epithelium

    Författare :Abeba Demelash; Göteborgs universitet; []
    Nyckelord :Thyroid; Apoptosis; Caspase; Calpain; Hydrogen peroxide; TGF-beta; Staurosporine; Selenium; Cytochrome c;

    Sammanfattning : Apoptosis or programmed cell death allows the multicellular organism to remove cells that are in excess or potentially dangerous. Apoptosis has to be strictly controlled, yet inappropriately activated or suppressed apoptototic may contribute to a variety of diseases, including cancer, autoimmune disorders and neurodegenerative conditions. LÄS MER

  4. 3. In vitro studies on the mechanisms of inhibited thyroidal iodide uptake and destructive thyroiditis as adverse effects of amiodarone and interferon-gamma

    Författare :Sofia Tedelind; Göteborgs universitet; []
    Nyckelord :thyroid; amiodarone; interferon-gamma; iodide transport; tight junction; mitochondria; endocytosis;

    Sammanfattning : The clinical use of the potent anti-arrhythmic drug amiodarone is limited due to adverse effects e.g. in the thyroid comprising both hypo- and hyperthyroidism. Amiodarone-induced thyroid dysfunction can occur in subjects with normal thyroid glands but also in those with an underlying thyroid abnormality resulting in an aggravation of the condition. LÄS MER

  5. 4. The importance of thyroid function for female reproduction

    Författare :Frida Hosseini Akram; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Thyroid dysfunction is one of the most common endocrine disorder. Thyroid dysfunction affects the female reproductive system and can be manifested by menstrual irregularities, pregnancy loss and infertility. Unexplained infertility has an incidence of 10 to 15 % worldwide. LÄS MER

  7. 5. The role of thyroid stimulating hormone receptor and novel candidate genes FAM13a and POM121c in adipocyte dysfunction

    Författare :Veroniqa Lundbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis aimed to investigate the role of thyroid stimulating hormone receptors (TSHRs) in adipose tissue (AT) and their role in AT dysfunction and obesity-related metabolic complications. Furthermore, we aimed to functionally evaluate novel candidate genes associated with insulin resistance, a marker of dysfunctional adipose tissue. LÄS MER