Sökning: "subsets"

Visar resultat 6 - 10 av 446 avhandlingar innehållade ordet subsets.

  1. 6. B cell subsets in autoimmune disease

    Författare :Katrin Habir; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : B lymphocytes are a type of white blood cells, belonging to the adaptive arm of the immune system and involved in creating immunological memory. B cells function in the humoral immune system by secreting antibodies which can bind pathogens to prevent them from doing further damage and to help other immune cells to target them. LÄS MER

  3. 7. Neutrophil subsets in airway inflammation and hyperreactivity

    Författare :Sandra Ekstedt; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Neutrophils are part of the first lines of defence against invading microbes. They play an essential role in antimicrobial host defence by recognizing microorganisms through the various receptors that can be expressed on their surfaces. LÄS MER

  4. 8. Immunoglobulin Gene Analysis in Chronic Lymphocytic Leukemia : Characterization of New Prognostic and Biological Subsets

    Författare :Gerard Tobin; Richard Rosenquist; Christer Sundström; Anna Laurell; Nicholas Chiorazzi; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Genetics; chronic lymphocytic leukemia; immunoglobulin genes; VH3-21; CDR3; P2X7; Genetik; Clinical genetics; Klinisk genetik;

    Sammanfattning : Recent studies have shown that the somatic mutation status of the immunoglobulin (Ig) VH genes can divide chronic lymphocytic leukemia (CLL) into two prognostic subsets, since cases with mutated VH genes display superior survival compared to unmutated cases. Biased VH gene usage has also been reported in CLL which may reflect antigen selection. LÄS MER

  5. 9. Exploring functional subsets of cancer-associated fibroblasts

    Författare :Michael Bartoschek; Avdelningen för translationell cancerforskning; []
    Nyckelord :;

    Sammanfattning : The tumor microenvironment consists of several interacting cell types. Cancer research focssed mainly on the malignant cell in the past. The importance of the tumor microenvironment is increasingly appreciated, as endothelial cells and immune cells were identified as targets for anti-tumor therapy. LÄS MER

  7. 10. Genetics and functions of innate-like lymphocyte subsets

    Författare :Julia Rolf; Göteborgs universitet; []
    Nyckelord :innate-like lymphocyte; CD1d; autoimmunity; genetic mapping; microarray; Salmonella infection;

    Sammanfattning : The immune system contains three different branches: innate immunity, adaptive immunity and innate-like lymphocytes that share properties both with the innate and adaptive immune cells. The innate-like lymphocytes have the capacity to rapidly become activated by invading pathogens and also to modulate immune responses and thereby inhibit or promote inflammation. LÄS MER