Sökning: "scoring functions"

Visar resultat 21 - 25 av 28 avhandlingar innehållade orden scoring functions.

  1. 21. Computer Simulation of Protein Tyrosine Phosphatase Reaction Mechanisms and Dihydrofolate Reductase Inhibition

    Författare :Karin Kolmodin; Ernst-Walter Knapp; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Cell and molecular biology; Cell- och molekylärbiologi; Cell and molecular biology; Cell- och molekylärbiologi; Molecular Biotechnology; Molekylär bioteknik;

    Sammanfattning : Protein tyrosine phosphatases catalyse the hydrolysis of phosphotyrosine residues in proteins, which is an important reaction in the cell signalling system. The three dimensional structure of such a protein tyrosine phosphatase has been used in a computational study of the reaction mechanism at the atomic level. LÄS MER

  3. 22. Controlling Fusarium Head Blight in oat

    Författare :Alfia Khairullina; Tillämpad biokemi; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; FHB; oat; UDP-glucosyltransferase; deoxynivalenol; mycotoxins; biocontrol; Clonostachys rosea; Fusarium head blight; Fusarium graminearum; endophytes;

    Sammanfattning : Oats (Avena sativa) is a versatile crop grown worldwide for animal feed and human consumption. Humanoat consumption has recently risen due to its various health benefits. However, oats are susceptible toFusarium head blight (FHB) caused by various Fusarium fungi. FHB reduces yield and leads to mycotoxinaccumulation. LÄS MER

  4. 23. Determination and use of radiobiological response parameters in radiation therapy optimization

    Författare :Panayiotis Mavroidis; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Radiotherapy optimization; tumour control; normal tissue complications; radiobiological treatment planning; biological models; dose-response parameters;

    Sammanfattning : Optimization of radiation therapy is critically dependent on the use of patient related information. For this reason, radiobiological models describing the dependence of tumour and normal tissue responses on the irradiated volume and the dose-time-fractionation schedule should be introduced. LÄS MER

  5. 24. Prediction of side effects from anticancer treatment with the purpose of increasing quality of life

    Författare :Delmy Oliva; Freddi Lewin; Charlotta Dabrosin; Lena Sharp; Lasse D Jensen; Eva Brun; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Cancer and its treatments can cause a variety of symptoms. Some of these symptoms are related to the disease and others are seen as a consequence of the treatment. Since patients experience side effects to different degrees despite undergoing the same treatment, it is hypothesized that there is a genetic factor. LÄS MER

  7. 25. Parallel target selection by trinucleotide threading

    Författare :Pawel Zajac; Joakim Lundeberg; Afshin Ahmadian; Mats Nilsson; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; trinucleotide threading; multiplex amplification; expression profiling; microarray; generic tag; short tandem repeat; microsatellite; electrophoresis; single nucleotide polymorphism; allelotyping; 454; Pyrosequencing; Genetic engineering including functional genomics; Genteknik inkl. funktionsgenomik;

    Sammanfattning : DNA is the code for all life. Via intermediary RNA the information encoded by the genome is relayed to proteins executing the various functions in a cell. Together, this repertoire of inherently linked biological macromolecules determines all characteristics and features of a cell. LÄS MER