Sökning: "normal tissue complications"

Visar resultat 1 - 5 av 68 avhandlingar innehållade orden normal tissue complications.

  1. 1. Improved dose response modeling for normal tissue damage and therapy optimization

    Författare :Magdalena Adamus-Górka; Bengt K. Lind; Anders Brahme; Panayiotis Mavroidis; Randall K. Ten Haken; Stockholms universitet; []
    Nyckelord :Normal tissue complications; radiobiological models; dose-response; volume effect; spinal cord; effective FSU size; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : The present thesis is focused on the development and application of dose response models for radiation therapy. Radiobiological models of tissue response to radiation are an integral part of the radiotherapeutic process and a powerful tool to optimize tumor control and minimize damage to healthy tissues for use in clinical trials. LÄS MER

  3. 2. Predicting Normal Tissue Complications after External Beam Radiation Therapy

    Författare :Caroline Olsson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

    Sammanfattning : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. LÄS MER

  4. 3. Predicting Normal Tissue Complications after External Beam Radiation Therapy

    Författare :Caroline Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : .... LÄS MER

  5. 4. On the biological response to different biomaterials under normal and irradiated conditions

    Författare :Louise Rydén; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biomaterials; bone; fibrosis; hydroxyapatite; inflammation; irradiation; Osseointegration; silicone; soft tissue; titanium;

    Sammanfattning : There are several challenges when introducing an implant into a host. Concerning soft tissues, major complications are fibrosis and capsule contracture, whereas for bone, failure of osseointegration may occur. LÄS MER

  7. 5. Interplay between hormones, nutrients and adipose depots in the regulation of insulin sensitivity : an experimental study in rat and human adipocytes

    Författare :Magdalena Lundgren; Jan Eriksson; Jonas Burén; Eva Degerman; Umeå universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; adipose tissue; cAMP; glucocorticoids; glucose; insulin; insulin resistance; lipolysis; subcutaneous fat; type 2 diabetes; visceral fat; Medicine; Medicin;

    Sammanfattning : Obesity and specifically central obesity is related to insulin resistance, type 2 diabetes and other components of the so-called metabolic syndrome. The aim of this study was to elucidate the interplay between hormones, nutrients and adipose depots in normal and insulin-resistant fat cell metabolism. LÄS MER