Sökning: "radiation therapy planning"
Visar resultat 21 - 25 av 73 avhandlingar innehållade orden radiation therapy planning.
21. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy
Sammanfattning : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. LÄS MER
22. Probabilistic machine learning methods for automated radiation therapy treatment planning
Sammanfattning : In this thesis, different parts of an automated process for radiation therapy treatment planning are investigated from a mathematical and computational perspective. Whereas traditional inverse planning is labor-intensive, often comprising several reiterations between treatment planner and physician before a plan can be approved, much of recent research have been aimed at using a data-driven approach by learning from historically delivered plans. LÄS MER
23. Biological optimization of angle of incidence and intensity modulation in breast and cervix cancer radiation therapy
Sammanfattning : Biological treatment optimization aim at improving radiation therapy by accounting for the radiobiological tumour and normal tissues response properties when optimizing the dose delivery. Generally traditional methods, using only dosimetrical measures, disregard the nonlinear radiation response of different tumours and normal tissues. LÄS MER
24. Development of analytical transport methods for biologically optimized light ion therapy
Sammanfattning : A general objective in the treatment of cancer is to eradicate the tumour cells without inducing severe complications in healthy normal tissue. The use of light ions for radiation therapy increases the possibility to deliver tumour suicidal doses with very low probability of normal tissue injury, not least in cases where the target is unresectable, radioresistant and located to near organs at risk. LÄS MER
25. Radiation burden from modern radiation therapy techniques including proton therapy for breast cancer treatment - clinical implications
Sammanfattning : The purpose of this thesis was to study the clinical implications of modern radiotherapy techniques for breast cancer treatment. This was investigated in several individual studies. LÄS MER