Sökning: "radiation therapy planning"

Visar resultat 21 - 25 av 73 avhandlingar innehållade orden radiation therapy planning.

  1. 21. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy

    Författare :Caroline Olsson; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; dose and side effect data; dose-volume response; fractionation effect; LQ model; sequential two-phase radiotherapy; head and neck cancer; parotid gland; xerostomia; pelvic radiotherapy; gynecological cancer; pubic bone; pain; data integration; xerostomia;

    Sammanfattning : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. LÄS MER

  2. 22. Probabilistic machine learning methods for automated radiation therapy treatment planning

    Författare :Tianfang Zhang; Jimmy Olsson; Steve Jiang; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Matematisk statistik; Mathematical Statistics;

    Sammanfattning : In this thesis, different parts of an automated process for radiation therapy treatment planning are investigated from a mathematical and computational perspective. Whereas traditional inverse planning is labor-intensive, often comprising several reiterations between treatment planner and physician before a plan can be approved, much of recent research have been aimed at using a data-driven approach by learning from historically delivered plans. LÄS MER

  3. 23. Biological optimization of angle of incidence and intensity modulation in breast and cervix cancer radiation therapy

    Författare :Brigida Costa Ferreira; Anders Brahme; Roger Svensson; Ion Christian Chiricuta; Stockholms universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; biological treatment planning; angle of incidence optimization; intensity modulation; breast and cervix cancer; Radiation biology; Strålningsbiologi;

    Sammanfattning : Biological treatment optimization aim at improving radiation therapy by accounting for the radiobiological tumour and normal tissues response properties when optimizing the dose delivery. Generally traditional methods, using only dosimetrical measures, disregard the nonlinear radiation response of different tumours and normal tissues. LÄS MER

  4. 24. Development of analytical transport methods for biologically optimized light ion therapy

    Författare :Johanna Kempe; Anders Brahme; Irena Gudowska; Naruhiri Matsufuji; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Radiotherapy; radiation quality; energy-range relations; light ion transport; pencil beam; Monte Carlo; Physics; Fysik; medicinsk strålningsfysik; Medical Radiation Physics;

    Sammanfattning : A general objective in the treatment of cancer is to eradicate the tumour cells without inducing severe complications in healthy normal tissue. The use of light ions for radiation therapy increases the possibility to deliver tumour suicidal doses with very low probability of normal tissue injury, not least in cases where the target is unresectable, radioresistant and located to near organs at risk. LÄS MER

  5. 25. Radiation burden from modern radiation therapy techniques including proton therapy for breast cancer treatment - clinical implications

    Författare :Anna M. Flejmer; Alexandru Dasu; Gunnar Adell; Olle Stål; Margaretha Stenmarker; Thomas Björk-Eriksson; Linköpings universitet; []
    Nyckelord :;

    Sammanfattning : The purpose of this thesis was to study the clinical implications of modern radiotherapy techniques for breast cancer treatment. This was investigated in several individual studies. LÄS MER