Sökning: "dose-volume response"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden dose-volume response.

  1. 1. Radiation Oncology Data and Modelling Side Effects after Radiation Therapy

    Detta är en avhandling från Göteborg : Chalmers University of Technology

    Författare :Caroline Olsson; Göteborgs universitet.; Gothenburg University.; [2012]
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dose and side effect data; dose-volume response; fractionation effect; LQ model; sequential two-phase radiotherapy; head and neck cancer; parotid gland; xerostomia; pelvic radiotherapy; gynecological cancer; pubic bone; pain; data integration;

    Sammanfattning : Although modern radiation therapy techniques have the ability to conform the dose distribution of ionizing radiation tightly around the volume to be treated, unwanted irradiation to surrounding organs remains a problem. The probability of a side effect arising in the normal tissue of a patient after radiation therapy can be modelled by sigmoid mathematical functions known as normal tissue complication probability (NTCP) models. LÄS MER

  2. 2. Towards eliminating pelvic bone pain after radiation therapy among long-term gynecological cancer survivors

    Detta är en avhandling från Göteborg : University of Gothenburg

    Författare :Ann-Charlotte Waldenström; Göteborgs universitet.; Gothenburg University.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pelvic radiotherapy; gynecological cancer; pelvic bone pain; dose-volume response;

    Sammanfattning : Aim: To investigate the prevalence of self-reported symptoms after pelvic radiation therapy among long-term gynecological cancer survivors, with special focus on pelvic bone pain, how it affects the daily life of the women and the relationship to absorbed doses. Methods: In an unselected, population-based study, gynecological cancer survivors from the Gothenburg and Stockholm regions, treated with pelvic radiation therapy between 1991 and 2003, were compared with a non-radiation-treated control population. LÄS MER

  3. 3. Towards better quality of life after radiation therapy by improved response modeling

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Oncology-Pathology

    Författare :Eleftheria Alevronta; Karolinska Institutet.; Karolinska Institutet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: To improve the quality of life of radiotherapy cancer survivors we need to improve our knowledge of the dose, volume and time-response relations of radiotherapy induced late effects. Aims: The aim of the thesis was to investigate predictors for normal-tissue complications of head and neck, and gynecological radiotherapy using response modeling. LÄS MER

  4. 4. Predicting Normal Tissue Complications after External Beam Radiation Therapy

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Oncology-Pathology

    Författare :Caroline Olsson; Göteborgs universitet.; Gothenburg University.; [2010]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NTCP; fractionation effects; radiobiological modelling; pubic bone pain;

    Sammanfattning : Although modern external beam radiation (EBRT) therapy has the ability to conform the dose tightly around the volume to be treated, unwanted irradiation to surrounding normal tissue is still a problem. The probability of a side effect arising in normal tissue after EBRT is commonly modelled by an s-shaped dose-volume response curve where dose or volume are plotted against response (i. LÄS MER

  5. 5. Towards Prevention of Pelvic Radiation Disease in Gynecological Cancer Survivors

    Detta är en avhandling från Stockholm : Karolinska Institutet, Dept of Oncology-Pathology

    Författare :Helena Lind; Karolinska Institutet.; Karolinska Institutet.; [2011]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Background: To improve the therapeutic ratio of radiation therapy, an increased knowledge of how dose distributions affect normal tissue outcomes is critically needed; however normal tissue outcomes in terms of self-reported atomized symptoms among gynecological cancer survivors are rare in the literature. Aims: To investigate the prevalence of self-reported symptoms and their impact on daily life among long-term gynecological cancer survivors previously treated with pelvic radiation therapy. LÄS MER