Sökning: "prostate zones"

Hittade 3 avhandlingar innehållade orden prostate zones.

1. 1. Identification of miRNA expression profiles for diagnosis and prognosis of prostate cancer

   Författare :Jessica Carlsson; Karin Klinga Levan; Björn Olsson; Gisela Helenius; Pernilla Wikström; Örebro universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; microRNAs; prostate zones; normalization; endogenous controls; Medicin; Medicine;

   Sammanfattning : Cancer of the prostate (CaP) is the most common malignancy diagnosed in men in the Western society. During the last years, prostate specific antigen (PSA) has been used as a biomarker for CaP, although a high PSA value is not specific for CaP. Thus, there is an urgent need for new and improved diagnostic markers for CaP. LÄS MER

3. 2. Protein expression in prostate cancer

   Författare :Helena Lexander; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Two-dimensional gel electrophoresis; protein expression; biomarker; Gleason grade; DNA-ploidy;

   Sammanfattning : The molecular pathology of prostate cancer (PCa) is complex and the pathways and the acquired molecular defects responsible for PCa initiation, development and progression are still largely unknown. Tumors of the prostate have an unpredictable behavior and in clinically detected cancers it is presently not possible to assess tumor aggressiveness. LÄS MER

4. 3. Sample preparation and mass spectrometry in proteome studies

   Författare :Daniel Hirschberg; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Proteome studies aim to link gene to function. Instead of screening for function in a specific protein as in classical protein chemistry, proteins are now screened against a specific phenotype, disease or metabolic state. LÄS MER