Sökning: "endogenous controls"

Visar resultat 1 - 5 av 127 avhandlingar innehållade orden endogenous controls.

  1. 1. Inflammatogenic properties of endogenous DNA

    Författare :Shahin Hajizadeh; Göteborgs universitet; []
    Nyckelord :Inflammation; mtDNA; oxidized DNA; SF; CSF; RA; dementia;

    Sammanfattning : Bacterial DNA and CpG-containing oligodeoxynucleotides (ODNs) induce host inflammatory responses as a result of their content of unmethylated ¡§CpG motifs¡¨. Since the CpG motifs in the mitochondrial (mt) genome are in this respect similar to bacterial DNA, in that they are non-methylated, we investigated whether mtDNA also displays inflammatogenic potential. LÄS MER

  3. 2. Identification of miRNA expression profiles for diagnosis and prognosis of prostate cancer

    Författare :Jessica Carlsson; Karin Klinga Levan; Björn Olsson; Gisela Helenius; Pernilla Wikström; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; microRNAs; prostate zones; normalization; endogenous controls; Medicin; Medicine;

    Sammanfattning : Cancer of the prostate (CaP) is the most common malignancy diagnosed in men in the Western society. During the last years, prostate specific antigen (PSA) has been used as a biomarker for CaP, although a high PSA value is not specific for CaP. Thus, there is an urgent need for new and improved diagnostic markers for CaP. LÄS MER

  4. 3. MicroRNA expression profiling in endometrial adenocarcinoma

    Författare :Sanja Jurcevic; Karin Klinga-Levan; Björn Olsson; Yvonne Wettergren; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Endometrial cancer; microRNA; BDII rat model; normalization; endogenous controls; Medicin; Medicine;

    Sammanfattning : .... LÄS MER

  5. 4. Analysis of Endogenous Particles in Exhaled Air

    Författare :Ann-Charlotte Almstrand; Göteborgs universitet; []
    Nyckelord :exhaled particles; time-of-flight secondary ion mass spectrometry; OPLS; airway closure; exhaled breath condensate; glutathione;

    Sammanfattning : Exhaled air contains non-volatile particulate material from the respiratory tract. The precise location in which exhaled particles are formed is unknown, and details on their chemical content are scarce. The aim of this work was to chemically characterize and to study the mechanisms of formation of endogenous particles in exhaled air. LÄS MER

  7. 5. Glutamatergic mechanisms in schizophrenia : role of endogenous kynurenic acid

    Författare :Linda K Nilsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Kynurenic acid, a tryptohan metabolite synthesised in astrocytes, is an endogenous antagonist at glutamate receptors, in particular it blocks the glycine site of the (NMDA)-receptor, and at the a7* nicotinic receptor. The compound has been found to be elevated in the cerebrospinal fluid (CSF) as well as in the postmortem prefrontal cortex of patients with schizophrenia. LÄS MER