Avancerad sökning

Visar resultat 16 - 20 av 150 avhandlingar som matchar ovanstående sökkriterier.

  1. 16. Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY

    Författare :Henriette Husum Bak-Jensen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Maternal deprivation; stress; mood stabilizing drugs; NPY; mood disorders; depression; anhedonia; Hinders Sensitive Line rats; Amygdala-kindling; microdialysis; RIA; histochemistry.;

    Sammanfattning : Experiences of early adverse life events are more frequent among adult depressed patients than healthy subjects. Studies with non-human primates and rats show that maternal deprivation leads to changes in hypothalamic-pituitary adrenal (HPA)-axis activity/reactivity and increased levels of anxiety and alcohol preference. LÄS MER

  3. 17. Fetal exposure to neurotropic drugs : neonatal effects and long-term outcome

    Författare :Lisa Forsberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic illness in pregnant women is common. In epilepsy, bipolar disorder (BD) or major depressive disorder (MDD), pharmacotherapy is often necessary. Some neurotropic drugs may have negative effects on children exposed in utero. LÄS MER

  4. 18. The rational use of drugs in a population of very old persons

    Författare :Maria Stella T Giron; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : This thesis investigated the use of drugs in a population of very old persons. The pattems of use, particularly of psychotropic drugs, and its appropriateness were assessed. Drug use was also assessed according to dementia diagnosis and in relation to the presence of psychiatric illnesses. LÄS MER

  5. 19. Prescribing drugs in primary health care - Thoughts, information strategy and outcome

    Författare :Ingmarie Skoglund; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Utilitarianism; prescribing medication; evidence-based medicine; general practitioner; pharmaceutical therapy; guide lines; drug information services; primary health care; multilevel models; pharmaceutical industry; attitudes; behaviour; public authority drug information; prompt and pragmatic benefit; drug and therapeutic committee; implementation;

    Sammanfattning : Aims: General aim; to investigate whether tailored evidence-based drug information provided to general practitioners can be implemented more effectively than evidence-based drug information provided as usual. Specific aims; to describe general practitioners’ (GPs) thoughts on prescribing medication and evidence-based drug information: to explore GPs’ attitudes on drug information: to investigate whether tailored evidence-based drug information can influence these attitudes differently or the prescribing behaviour more effectively than drug information provided as usual. LÄS MER

  7. 20. Consequences of inadequate use of glucose lowering drugs and associated risk factors

    Författare :Lotta Walz; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Diabetes Mellitus is characterized by chronically elevated blood glucose levels, hyperglycaemia. Consistent adherence to appropriate glucose-lowering drug therapy is fundamental to prevent disease progression, diabetes-related complications and premature death. LÄS MER