Sökning: "Hinders Sensitive Line rats"

Hittade 2 avhandlingar innehållade orden Hinders Sensitive Line rats.

  1. 1. Maternal deprivation and mood stabilizing drugs : effects on rat brain NPY

    Författare :Henriette Husum Bak-Jensen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Maternal deprivation; stress; mood stabilizing drugs; NPY; mood disorders; depression; anhedonia; Hinders Sensitive Line rats; Amygdala-kindling; microdialysis; RIA; histochemistry.;

    Sammanfattning : Experiences of early adverse life events are more frequent among adult depressed patients than healthy subjects. Studies with non-human primates and rats show that maternal deprivation leads to changes in hypothalamic-pituitary adrenal (HPA)-axis activity/reactivity and increased levels of anxiety and alcohol preference. LÄS MER

  2. 2. Antidepressive and antipsychotic treatments : effects on nerve growth factor and brain-derived neurotrophic factor in rat brain

    Författare :Francesco Angelucci; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Recently it has been reported that depression and schizophrenia, the two major psychiatric disorders, are characterized by loss of neurons in specific brain regions. Nerve growth factor (NGF) and brain-derived neurotrophic factor (BDNF) are proteins involved in neuronal survival and plasticity of dopaminergic, cholinergic and serotonergic neurons in the central nervous system (CNS). LÄS MER