Sökning: "platelet activating factor"

Visar resultat 6 - 10 av 40 avhandlingar innehållade orden platelet activating factor.

  1. 6. Platelet-activating factor and lysophospatidylcholine in oxidized low density lipoprotein-mediated immune activation

    Författare :Yihui Huang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :atherosclerosis; oxidized LDL; platelet-activating factor PAF ; Iysophosphatidylcholine LPC ; anti-MHC class II antibodies; antibody; T cells; cytokine; IFN-[gamma]; IL-6; IL-4; TNF-[alpha]; a PAF specific receptor antagonist-WEB2170;

    Sammanfattning : Inflammation is a risk factor for development of cardiovascular disease, as in addition to known risk factors such as hypertension, hyperlipidemia, smoking and diabetes. Patients with inflammatory diseases including SLE have an enhanced risk of cardiovascular disease. LÄS MER

  3. 7. Gastrointestinal mucosal protective mechanisms : Mudolatory effects of Heliobacter pyroli on the gastric mucus gel barrier and mucosal blood flow in vivo

    Författare :Christer Atuma; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mucus gel layer; mucosal blood flow; mucus thickness; chronic infection; rat; platelet activating factor; mast cell; nitric oxide; nitric oxide synthase; ketotifen; intra-vital microscopy; microelectrode; laser-Doppler flowmetry; L-NNA; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

    Sammanfattning : The gastrointestinal mucus gel layer and blood flow are two important mechanisms for protection at the pre-epithelial and sub-epithelial levels, respectively. Helicobacter pylori might circumvent these mechanisms and elicit a chronic inflammatory response with consequent ulcers in the stomach and duodenum. LÄS MER

  4. 8. Mechanism of F-actin crosslinking by filamin A and the anti-inflammatory functions of plasma gelsolin in bodily fluids

    Författare :Teresia Magnuson Osborn; Göteborgs universitet; []
    Nyckelord :Cytoskeleton; Crosslinking; F-actin; Filamin; Gelsolin; Inflammation; Plasma; Platelet-activating factor; Lysophosphatidic acid; Rheumatoid arthritis;

    Sammanfattning : Gelsolin (GSN) and filamin A (FLNa) are two actin-binding proteins discovered in our laboratory over 30 years ago. GSN is a calcium-activated actin severing and barbed end capping protein that is expressed as both intracellular and extracellular (plasma gelsolin, pGSN) isoforms. LÄS MER

  5. 9. Formation and Relevance of Platelet Subpopulations

    Författare :Anna Södergren; Sofia Ramström; Karin Öllinger; Riitta Lassila; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Platelets are important players in the hemostatic system, acting as guardians of vessel integrity. When they come across a breach in the vessel wall, they quickly adhere to the damaged surface, secrete activating and adhesive compounds from their secretory granules, recruit additional platelets into a growing platelet plug and support the action of the coagulation system. LÄS MER

  7. 10. Characterisation of compounds with platelet activating factor related activity from Polypodiun decumanum, a fern with clinical use in psoriasis

    Författare :Mervi Vasänge; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER