Sökning: "mucus thickness"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden mucus thickness.

1. 1. Gastrointestinal mucosal protective mechanisms : Mudolatory effects of Heliobacter pyroli on the gastric mucus gel barrier and mucosal blood flow in vivo

   Författare :Christer Atuma; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology and anatomy; mucus gel layer; mucosal blood flow; mucus thickness; chronic infection; rat; platelet activating factor; mast cell; nitric oxide; nitric oxide synthase; ketotifen; intra-vital microscopy; microelectrode; laser-Doppler flowmetry; L-NNA; Fysiologi och anatomi; Physiology and pharmacology; Fysiologi och farmakologi; Physiology; fysiologi;

   Sammanfattning : The gastrointestinal mucus gel layer and blood flow are two important mechanisms for protection at the pre-epithelial and sub-epithelial levels, respectively. Helicobacter pylori might circumvent these mechanisms and elicit a chronic inflammatory response with consequent ulcers in the stomach and duodenum. LÄS MER

3. 2. Citrobacter rodentium and Escherichia coli interactions with mucus producing colonic epithelical cells

   Författare :Sinan Sharba; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; A E pathogens; cytokines; epithelium; mitochondria; mucus;

   Sammanfattning : The epithelial cells together with the mucus layer protect the host from noxious luminal substances and pathogenic invasion. Pathogens have evolved numerous strategies to circumvent these barriers and mount infection. C. rodentium is a murine model for the attaching and effacing intestinal E. LÄS MER

4. 3. Mucus and mucins during gastrointestinal infections

   Författare :Nazanin Navabi; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mucin; gastrointestinal cell lines; mucus layer; secreted mucin; cell surface mucin; H. pylori; C. rodentium; ETEC; mucin secretion; goblet cells;

   Sammanfattning : The gastrointestinal tract is protected by a continuously secreted mucus layer formed by mucin glycoproteins. The mucus layer and mucins change dynamically during infection. The main focus of this thesis was to investigate the changes in mucin and the mucus layer in the gastrointestinal tract during infection with the gastrointestinal pathogens C. LÄS MER

5. 4. Nitrate, Nitrite and Nitric Oxide in Gastric Mucosal Defense

   Författare :Joel Petersson; Lena Holm; Jon Lundberg; Mia Phillipson; Matthew Grisham; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; dietary nitrate; mucus gel layer; mucosal blood flow; mucus thickness; laser-Doppler flowmetry; mucosal damage; intra-vital microscopy; mucosal permeability; Physiology; Fysiologi;

   Sammanfattning : The human stomach normally contains high levels of bioactive nitric oxide (NO). This NO derives from salivary nitrate (NO3-) that is converted to nitrite (NO2-) by oral bacteria and thereafter non-enzymatically reduced in the acidic gastric lumen to NO. LÄS MER

7. 5. Helicobacter pylori and Gastric Protection Mechanisms : An in vivo Study in Mice and Rats

   Författare :Johanna Henriksnäs; Lena Holm; Lars Engstrand; Erik Persson; Lars Fändriks; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Physiology; mucus gel layer; mucosal blood flow; mucus thickness; intra-vital microscopy; laser-Doppler flowmetry; pH-sensitive microelectrode; nitric oxide; Helicobacter pylori; bicarbonate secretion; mouse model; Fysiologi; Physiology; Fysiologi;

   Sammanfattning : The stomach is frequently exposed to hazardous agents and to resist this harsh environment, several protective mechanisms exist. Of special interest is the gastric pathogen Helicobacter pylori which causes gastritis, ulcers and cancer but the mechanism leading to these diseases are still unclear. However it is very likely that H. LÄS MER