Sökning: "platelet activating factor"

Visar resultat 21 - 25 av 40 avhandlingar innehållade orden platelet activating factor.

  1. 21. Mechanisms of inflammatory lung injury : Studies in isolated perfused rat lungs

    Författare :Anders Ljungman; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Isolated perfused rat lungs (IPRLs) were used to study mechanisms andmediators of lung injury due to (i) ischemia-reperfusion (IR) and (ii) endotoxin. To investigate the role of polymorphonuclear neutrophils (PMNs) in IR injury, PMNs were added to the perfusate of IPRLs subjected to IR. LÄS MER

  3. 22. Phospholipase A2 expression in the human nasal mucosa

    Författare :John Lindbom; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Phospholipase A2 (PLA2) is a superfamily of enzymes that play a key role in inflammation by releasing arachidonic acid for the synthesis of eicosanoids and lysophospholipid for the synthesis of platelet-activating factor (PAF). On the other hand, several members of the PLA2 family (VIIA, VIIB, VIIIA and VIIIB) are able to degrade PAF and are therefore potentially important anti-inflammatory enzymes. LÄS MER

  4. 23. Augmentation of vital organ blood flow during experimental cardiopulmonary resuscitation

    Författare :Rolf Gedeborg; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cardiac arrest; cardiopulmonary resuscitation; epinephrine; high-dose epinephrine; buffer; cerebral blood flow; post-resuscitation period; aortic occlusion; Kirurgi; Surgery; Kirurgi; Anestesiologi; Anaesthesiology;

    Sammanfattning : Clinical outcome from cardiac arrest remains poor. If the time from arrest to restoration of spontaneous circulation can be shortened and resuscitation techniques improved so that higher blood flow and oxygen delivery to vital organs is achieved, it is possible that the outcome from cardiac arrest could improve. LÄS MER

  5. 24. Phospholipase A2 expression in the human nasal mucosa

    Författare :John Lindbom; Roger Sundler; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Phospholipase A2 (PLA2) is a superfamily of enzymes that promote inflammation by releasing arachidonic acid for the synthesis of eicosanoids and lysophospholipid for the synthesis of platelet-activating factor (PAF). On the other hand, several members of the PLA2 family (VIIA, VIIB, VIIIA and VIIIB) are able to degrade PAF and are therefore potentially important anti-inflammatory enzymes. LÄS MER

  7. 25. Neutrophil Function and Signaling Induced by Ligands for the Formyl Peptide Receptor 2

    Författare :André Holdfeldt; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neutrophils; G-protein-coupled receptors; Formyl peptide receptor 2;

    Sammanfattning : Neutrophil pattern recognition receptors belonging to the G-protein coupled receptor (GPCR) family play a role in the processes of initiation as well as resolution of inflammatory processes. Formyl peptide receptor 2 (FPR2) in neutrophils is such a receptor and plays an important role in inflammation. LÄS MER