Sökning: "platelet-activating factor PAF"
Visar resultat 1 - 5 av 20 avhandlingar innehållade orden platelet-activating factor PAF.
1. Platelet-activating factor, intestinal epithelial cells, and Chron's disease : An experimental study
Sammanfattning : Platelet-activating factor (PAF-acethcr, 1-0-alky l-2-acetyl-s n- glycero-3- phosphocholine), is a potent inflammatory mediator that can be formed by a variety of cells and tissues. In the present investigation, the content of PAFacether was determined in mucosal biopsies from the ileum and colon of patients with Crohn's disease and control patients. LÄS MER
2. Role of platelet-activating factor in sepsis and shock : an experimantal study
Sammanfattning : Objectives: To study the role of platelet-activating factor (PAF) on cardiovascular and pulmonary dysfunction in sepsis and shock.Design: Experimental study. Setting: Trauma research unit, university department of surgery, Sweden.Material: 76 juvenile domestic pigs. LÄS MER
3. Platelet-activating factor and lysophospatidylcholine in oxidized low density lipoprotein-mediated immune activation
Sammanfattning : Inflammation is a risk factor for development of cardiovascular disease, as in addition to known risk factors such as hypertension, hyperlipidemia, smoking and diabetes. Patients with inflammatory diseases including SLE have an enhanced risk of cardiovascular disease. LÄS MER
4. Gastrointestinal mucosal protective mechanisms : Mudolatory effects of Heliobacter pyroli on the gastric mucus gel barrier and mucosal blood flow in vivo
Sammanfattning : The gastrointestinal mucus gel layer and blood flow are two important mechanisms for protection at the pre-epithelial and sub-epithelial levels, respectively. Helicobacter pylori might circumvent these mechanisms and elicit a chronic inflammatory response with consequent ulcers in the stomach and duodenum. LÄS MER
5. Mechanism of F-actin crosslinking by filamin A and the anti-inflammatory functions of plasma gelsolin in bodily fluids
Sammanfattning : Gelsolin (GSN) and filamin A (FLNa) are two actin-binding proteins discovered in our laboratory over 30 years ago. GSN is a calcium-activated actin severing and barbed end capping protein that is expressed as both intracellular and extracellular (plasma gelsolin, pGSN) isoforms. LÄS MER