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1. 1. Neuroprotective and regenerative actions of GDNF and neurturin on nigral dopamine neurons in rat models of Parkinson’s disease – Prospects for clinical use of neurotrophic factors in neurodegenerative disorders

   Författare :Carl Rosenblad; Neurobiologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neurophysiology; neuropsychology; Neurology; striatum; substantia nigra; dopamine; GDNF; neurturin; sprouting; neuroprotection; forelimb akinesia; rotation; tyrosine hydroxylase; transplantation; Neurologi; neuropsykologi; neurofysiologi;

   Sammanfattning : Parkinson’s disease is characterized by progressive degeneration of the nigrostriatal dopamine system, which results in tremor, rigidity, akinesia and postural abnormalities. New therapeutic strategies are aimed at halting the neurodegenerative process or restoring the system by transplantation of fetal dopamine neurons. LÄS MER