Sökning: "multi-resistant bacteria"

Visar resultat 6 - 10 av 16 avhandlingar innehållade orden multi-resistant bacteria.

  1. 6. Colonization, infection and dissemination in intensive care patients

    Författare :Christina Agvald-Öhman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Colonization; multi-resistant bacteria; dissemination; intensive care unit; invasive Candida infection;

    Sammanfattning : Nosocomial infections are a substantial problem in hospitals all over the world and the incidence is among the highest in the intensive care unit, affecting mortality and morbidity for the individual patient and cost for the society. In order to prevent these infections it is important to gain knowledge about colonization and infection pathways as well as about bacterial dissemination between patients. LÄS MER

  3. 7. Identification of novel antibiotic resistance genes through the exploration of mobile genetic elements

    Författare :Mohammad Razavi; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Environment; Metagenomics; Antibiotic resistance; Mobile genetic elements; Insertion sequences; Integron; Resistome; Next-generation sequencing;

    Sammanfattning : Backgrounds and aims: The evolution of multi-resistant pathogens is seriously threatening our ability to provide modern healthcare. Many of the mobile resistance factors in clinics appear to originate from environmental bacteria. LÄS MER

  4. 8. Anti-Virulence Strategy Targeting Sortase A, A Structural Investigation of the Sortase A Enzyme, and the Identification, Synthesis, and Evaluation of Sortase A Inhibitors

    Författare :Ivana Uzelac; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Kemi;

    Sammanfattning : The emergence of multi-resistant bacteria and their continuous spread is one of the greatest challenges when treating bacterial infections. Increased understanding of bacterial pathogenesis has revealed new strategies for treating bacteria-mediated diseases. LÄS MER

  5. 9. Microgels as Carriers for Antimicrobial Peptides : Surface-bound microgels, and factors affecting peptide interactions

    Författare :Lina Nyström; Martin Malmsten; Per Hansson; L. Andrew Lyon; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Antimicrobial peptides; Biomaterial coating; Drug delivery; Host defence peptides; Microgels; pH-responsive; Surface-bound; Pharmaceutical Physical Chemistry; Farmaceutisk fysikalisk kemi;

    Sammanfattning : With a growing number of multi-resistant bacteria against conventional antibiotics, there is an urgent need to identify new antimicrobial therapeutics. One example that has gained considerable interest is antimicrobial peptides (AMPs). LÄS MER

  7. 10. Diastereomeric Effects in DNA Binding – Biological and Biophysical Studies on Ruthenium Complexes

    Författare :Anna Mårtensson; Chalmers tekniska högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; neighbor interaction; spectroscopy; diastereomeric; kinetics; antimicrobial activity; ruthenium; calorimetry; intercalation; DNA; enantiomer;

    Sammanfattning : Organic molecules, such as glucose and amino acids, are most often chiral. This means that their mirror-images are different, in the same way a left and a right hand are different from each other. For example, the DNA double helix in its standard form twists like a right-handed screw. LÄS MER