Sökning: "interactions of mucins"

Visar resultat 1 - 5 av 23 avhandlingar innehållade orden interactions of mucins.

  1. 1. Analytical approaches to the study of mucin glycosylation

    Författare :Kristina A Thomsson; Göteborgs universitet; []
    Nyckelord :mucins; O-linked glycosylation; mass spectrometry; cystic fibrosis; salivary mucins; sulfated oligosaccharides.;

    Sammanfattning : Mucins constitute the major protein component of the mucus layer, which covers the epithelial surfaces of the respiratory, the gastrointestinal and the genitourinary tracts. Mucins carry O-linked oligosaccharides which contribute to the molecule by 50-80 weight percent, and these can be highly diverse, with 50-150 different oligosaccharides found on a purified mucin population. LÄS MER

  3. 2. Interactions of Mucins with Biopolymers and Drug Delivery Particles

    Författare :Olof Svensson; Malmö högskola; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mucin; chitosan; lactoperoxidase; multilayer; mucoadhesion; nanoparticles; ellipsometry;

    Sammanfattning : The main components in the mucous gels apart from water are mucins, which are proteins with high molecular weights and an abundance of negatively charged oligosaccharide side chains. The aim of the investigations was to characterize interactions between mucins and other proteins that are present in the mucous gel, and also between mucins and components used in pharmaceutical formulations. LÄS MER

  4. 3. Properties of Interfacial Proteinaceous Films with Emphasis on Oral Systems

    Författare :Cecilia Hahn Berg; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; Livsmedelsteknik; trypsin; SDS elutability; statherin; salivary proteins; salivary pellicle; proline-rich proteins; plaque control; mucins; microbial adhesion; lubrication; krillase; intraoral friction; hydroxyapatite; gelatin; exchange; enzymes; ellipsometry; dental plaque; degradation; colloidal probe; calcium-induced precipitation; adsorption; atomic force microscopy; total internal reflectance fluorescence spectroscopy;

    Sammanfattning : The present thesis addresses three issues related to proteinaceous films at solid/liquid interfaces: adsorption, lubrication and enzymatic interactions. Most of the work has been devoted to oral systems. In addition, gelatin has been investigated as a model protein. LÄS MER

  5. 4. The Role of FCGBP in Mucus - Structure, Processing and Function

    Författare :Erik Ehrencrona; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Mucus; FCGBP; IgG; IBD; COPD; Mucins; Disulphide; GDPH;

    Sammanfattning : In this thesis, a bottom-up approach was used to study the IgG Fc-binding protein (FCGBP), which next to the MUC2 mucin is the second main component of secreted mucus in small intestine and colon. FCGBP is also found in airways during inflammatory conditions with static mucus. LÄS MER

  7. 5. Mucins, Cystic Fibrosis and PDZ protein interactions

    Författare :Emily Malmberg; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Mucin; PDZ; transmembrane; MUC1; Cystic Fibrosis; clathrin; CFTR; PDZK1; Bcr; endocytosis; MUC17;

    Sammanfattning : Cystic Fibrosis (CF) is caused and characterized by mutations in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene. The dominating feature of the disease is mucus accumulation on mucosal surfaces, but no direct functional connection between mucus and CFTR is known. LÄS MER