Sökning: "insulin-like growth factor I IGF-I"
Visar resultat 1 - 5 av 93 avhandlingar innehållade orden insulin-like growth factor I IGF-I.
Sammanfattning : The aim of this thesis was to investigate the role of insulin-like growth factor-I (IGF-I) and interleukin-6 (IL-6) in the regulation of metabolism and body fat mass. Circulating IGF-I is mainly liver derived, while a large part of circulating IL-6 is produced by adipose tissue. LÄS MER
Sammanfattning : The insulin-like growth factor (IGF) system demonstrates numerous actions during neoplastic growth and is therefore an interesting target with potential clinical implications. While numerous studies have established important roles of the IGF system in regulating cellular growth and survival of several tumor forms, very limited reports exist regarding its role in renal cell carcinoma (RCC). LÄS MER
Sammanfattning : Growth hormone (GH) may exert direct growth-promoting and metabolic actions on target tissues, but most of its effects are mediated by circulating (endocrine) or local (auto-/paracrine) insulin-like growth factor-I (IGF-I). The GH/IGF-I system has an important role during cardiac development and for maintaining the structure and function of the heart. LÄS MER
Sammanfattning : Growth hormone (GH) exerts major effects on body growth and metabolism. Insulin-like growth factor (IGF) is expressed in response to GH and is known to mediate many of the effects of GH. The largest expression of IGF is found in the liver although it is expressed in virtually every tissue of the body. LÄS MER
5. New neurons and astrocytes in the adult brain. Studies on adult rat neural progenitors in vivo and in vitro with special reference to the effects of IGF-I and CNTF regarding proliferation and lineage determination
Sammanfattning : The hippocampal dentate gyrus in several species, including man, continues to produce new neurons and glial cells in adulthood. The generation of new neurons and glial cells in the adult hippocampus is under strict regulation. Two major events of significance for cell genesis from progenitor cells are proliferation and lineage determination. LÄS MER