Sökning: "inflammatory diseases"

Visar resultat 16 - 20 av 830 avhandlingar innehållade orden inflammatory diseases.

  1. 16. Studies on neurotrophins in inflammatory pulmonary diseases

    Författare :Charlotta Dagnell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma, sarcoidosis and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases, all being characterized by tissue inflammation, tissue damage (airway remodeling) and loss of lung function. In order to increase possibilities to find new biomarkers, drug targets and better treatment options for the patients, further research on the underlying mechanisms driving the inflammation and airway remodeling in these diseases are required. LÄS MER

  3. 17. Immunogenicity of biopharmaceuticals in chronic inflammatory diseases

    Författare :Christina Hermanrud; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Multiple sclerosis (MS) and rheumatoid arthritis (RA) are chronic inflammatory diseases where genetic and environmental factors influence the pathogenesis. MS is a disease of the central nervous system, while RA primarily affects the joints. LÄS MER

  4. 18. Evaluation of biomarkers in chronic inflammatory diseases

    Författare :Zahra Golabkesh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The overall aim of this thesis was to assess the role of biomarkers in chronic inflammatory disease. The goal of the first study was to investigate the association of sIL-6R and sgp130 levels and risk of first myocardial infarction (MI), and to explore the potential interaction between these two biomarkers in association with risk of MI. LÄS MER

  5. 19. Plasminogen : a novel inflammatory regulator that promotes wound healing

    Författare :Yue Shen; Tor Ny; Gunilla Høyer-Hansen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Plasminogen; inflammation; wound healing; diabetic wounds; tympanic membrane perforations; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : The plasminogen activator (PA) system has been shown to be intimately involved in wound healing. However, the role of this system in the initiation and resolution of inflammation during healing process remained to be determined. LÄS MER

  7. 20. Microcirculation, Mucus and Microbiota in Inflammatory Bowel Disease

    Författare :Olof Schreiber; Lena Holm; Mia Phillipson; Henrik Sjövall; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; inflammatory bowel diseases; experimental colitis; DSS; TNBS; colonic mucosal blood flow; laser-doppler flowmetry; colonic mucus thickness; MUC2; colonic mucosal barrier function; iNOS; eNOS; probiotics; Lactobacilli; Lactobacillus reuteri; colonic microbiota; T-RFLP; bacterial translocation; intravital microscopy; P-selectin; leukocyte recruitment; platelet recruitment; Physiology; Fysiologi; Physiology; Fysiologi;

    Sammanfattning : Inflammatory bowel diseases, (IBD), are a group of chronic disorders of the gastro-intestinal tract, and include Crohn’s disease (CD) and Ulcerative Colitis (UC). The pathogenesis is not known, but involves at least in part a loss of tolerance towards the commensal colonic microbiota. LÄS MER