Sökning: "immunoglobulin superfamily"

Visar resultat 1 - 5 av 18 avhandlingar innehållade orden immunoglobulin superfamily.

  1. 1. A study of the cytoplasmic domains of C-CAM isoforms : calmodulin binding and phosphorylation

    Författare :Magnus Edlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :adhesion molecules; adhesion regulation; BGP; Bgp; biliary glycoprotein; Calcium; Calmodulin; CaM; CAMs; carcinoembryonic antigen gene family; C-CAM; CEA; cell adhesion; Immunoglobulin super-family; PKC; protein kinase C.;

    Sammanfattning : C-CAM, a member of the Immunoglobulin Superfamily, was originally identified as an intercellular adhesion molecule, and can mediate cell-cell adhesion by homophilic binding. However, it also appears in high concentrations in luminal, microvillar surfaces. LÄS MER

  3. 2. Virion- and VAP-receptor recognition in the human adenovirus type 2 system

    Författare :Eduardo Rodriguez; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; T7pol-M13; adenovirus fiber shaft fragment; receptor recirculation; lysosomotropic agents; Adenovirus; HeLa cells; Microbiology; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : This thesis is focused on the early steps of a complex virus-cell interaction. The human adenovirus type 2 (HAdV-2) infects permissive cells, by first recognizing a protein of the immunoglobulin superfamily that serves as the Coxsackie and adenovirus receptor (CAR). This attachment step is mediated by the adenovirus fiber protein. LÄS MER

  4. 3. Inhibitory receptors of natural killer cells : specificity and regulation

    Författare :Mats Alheim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Immunological surveillance of organs and tissues for pathogens and transformed cells by immune cells and their soluble mediators is of outmost importance for the well-being of the host. The natural killer (NK) cell is an example of such an immune cell. LÄS MER

  5. 4. Hemolin expression during Cecropia development and its effect on malaria parasites

    Författare :Yohannes Assefaw-Redda; Ingrid Faya; Lage Cerenius; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Genetics; Genetik;

    Sammanfattning : Hemolin is a lepidopteran member of the immunoglobulin superfamily, initially isolated from the giant silkmoth Hyalophora cecropia. Hemolin is also induced by stimulation with microbial cell wall components and was recently shown to be strongly upregulated by baculovirus and double stranded RNA. LÄS MER

  7. 5. Studies on CAR and CLMP : two proteins of epithelial tight junctions

    Författare :Elisabeth Raschperger; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Tight junctions are important structures for the function of epithelial cells. They are composed of multi-protein complexes that connect the plasma membranes of two adjacent epithelial cells to each other and function as paracellular barriers, which regulate flux of ions, solutes, proteins and cells across the epithelium. LÄS MER