Sökning: "imatinib mesylate"

Visar resultat 6 - 8 av 8 avhandlingar innehållade orden imatinib mesylate.

  1. 6. Flexible parametric models for cancer patient survival : loss in expectation of life and further developments

    Författare :Hannah Bower; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Population-based cancer studies can contribute to a better understanding of cancer patient survival. The general aim of this thesis was to develop and apply statistical methods for population-based cancer studies to ensure understanding in this area. In any analysis setting, it is important that the statistical methods are appropriate. LÄS MER

  3. 7. Cardiovascular role of PDGF-B in development and disease. Studies in genetically engineered mice

    Författare :Henrik Nyström; Göteborgs universitet; []
    Nyckelord :atherosclerosis; cardiovascular disease; cell retention; in vivo physiology; neointimal hyperplasia; PDGF; transgenic mice; vascular function; vascular smooth muscle cell;

    Sammanfattning : Platelet-derived growth factor B (PDGF-B) is vital for microvascular development, and retention of PDGF-B to extracellular matrix (ECM) is important in this process. However, the role and source of PDGF-B in development of macrovascular function is disputed. LÄS MER

  4. 8. Uveal melanoma and macular degeneration : molecular biology and potential therapeutic applications

    Författare :Mario A Economou; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Uveal melanoma; exudative AMD; IGF-1R; c-Met; prognostic markers; metastasis; oral treatment; VEGF;

    Sammanfattning : Uveal melanoma is the most common primary intraocular malignant tumor in adults with 30% to 50% of patients that ultimately succumb to metastatic disease, mainly to the liver. Although new diagnostic and therapeutic tools have been developed during the most recent years, only the eye conservation rate has been achieved, while the survival rate remains poor. LÄS MER