Sökning: "CD8 T-cells"

Visar resultat 1 - 5 av 260 avhandlingar innehållade orden CD8 T-cells.

  1. 1. Generation of Therapeutic T Cells for Prostate Cancer

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Ole Forsberg; Uppsala universitet.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; T cells; dendritic cells; peptides; cytomegalovirus; adenovirus; immunotherapy; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi; Klinisk immunologi; Clinical Immunology;

    Sammanfattning : The work presented herein focuses on the activation of the adaptive immune system in order to develop T cell-based immunotherapy for viral infections and cancer. The main goal was to identify and activate viral or tumoral antigen-specific T cells by using different identification, isolation and stimulation techniques. LÄS MER

  2. 2. Human intraepithelial lymphocytes : a comparative study of phenotype, morphology, and functional properties of intraepithelial lymphocytes in gut and oral mucosa

    Detta är en avhandling från Umeå : Umeå universitet

    Författare :Carina Lundqvist; Umeå universitet.; [1995]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human intraepithelial lymphocytes; alimentary tract; intestinal epithelium; gut luminal antigens; gingiva; γδ T cells; immunoelectron microscopy; cytokine mRNA; RT-PCR; extrathymic T cell maturation; RAG-1; periodontitis; mucosal immune system; CD4-CD8- αβ T cells; CD8 γδ T cells;

    Sammanfattning : Human intraepithelial lymphocytes (IEL) constitute a unique cell population situated in the first line of defense of the alimentary tract. Here they are continuously exposed to a massive antigenic load of high complexity. However, different conditions prevail along the alimentary tract. LÄS MER

  3. 3. Infection induced chronic inflammation and it's association with prostate cancer initiation and progression

    Detta är en avhandling från Örebro : Örebro universitet

    Författare :Sabina Davidsson; Örebro universitet.; [2013]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Prostate cancer; chronic inflammation; CD4 helper T cells; CD8 cytotoxic T cells; regulatory T cells; Propionibacterium acnes; Medicin; Medicine;

    Sammanfattning : An association between cancer development and inflammation has long been suggested. Approximately 20% of all human cancers in adults are assumed to result from chronic inflammation. The aim of this thesis was to investigate if infection-induced chronic inflammation plays a role in prostate carcinogenesis. LÄS MER

  4. 4. Regulatory CD4+FOXP3+ T cells in Helicobacter pylori-induced disease

    Detta är en avhandling från Örebro : Örebro universitet

    Författare :Bert Kindlund; Göteborgs universitet.; Gothenburg University.; [2009]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Regulatory T cells; Helicobacter pylori; duodenal ulcer; gastric cancer; FOXP3;

    Sammanfattning : Helicobacter pylori colonize the gastric or duodenal mucosa of approximately half of the worlds’ population. Although most individuals are asymptomatic, H. pylori infection cause peptic ulcers or gastric cancer in 10-15 % and 1-2 %, respectively, of the infected individuals. LÄS MER

  5. 5. Cellular Immune Responses to Cytomegalovirus

    Detta är en avhandling från Uppsala : Acta Universitatis Upsaliensis

    Författare :Anna Karin Lidehäll; Uppsala universitet.; [2008]
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytomegalovirus; cellular immunology; infection; immune responses; congenital infection; CD4 T cells; CD8 T cells; immunosuppressed; MEDICINE Microbiology; immunology; infectious diseases Immunology Clinical immunology; MEDICIN Mikrobiologi; immunologi; infektionssjukdomar Immunologi Klinisk immunologi;

    Sammanfattning : Cytomegalovirus (CMV) is a widespread infection affecting 50-90% of the human population. A typical silent primary infection is followed by life-long persistence in the host under control by virus-specific CD8 (“killer”) and CD4 (“helper”) T cells. LÄS MER