Sökning: "glycolipid receptor"

Hittade 5 avhandlingar innehållade orden glycolipid receptor.

  1. 1. Diversity of CD1d-restricted natural killer T cells

    Författare :Markus Sköld; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; serology; Immunology; autoreactive; Ly49 receptor; CD1d; NKT cell; transplantation; Immunologi; serologi;

    Sammanfattning : The present study deals with natural killer (NK) T cells restricted to the antigen presenting molecule CD1d. NKT cells have been suggested to play a role in many diverse immunological situations such as clearance of different pathogens, protection against certain tumors, regulation of autoimmune reactions and as a link between innate and adaptive immune responses. LÄS MER

  3. 2. Studies on pneumococcal polysaccharides and their effect on immune cells

    Författare :Marianne Sundberg Kövamees; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Streptococcus pneumoniae is a major cause of morbidity and mortality in children and adults worldwide. The spectrum of infections caused by Streptococcus pneumoniae is well-characterized. LÄS MER

  4. 3. Gastrointestinal norovirus infections and the development of the next generation of mucosal vaccines

    Författare :Inga Rimkute; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; human norovirus; gastrointestinal infection; mucosal vaccine; subcomponent vaccine; human intestinal enteroids; histo-blood group antigens; lipidomics; glycoproteomics; glycosphingolipids;

    Sammanfattning : Human norovirus (HuNoV) is the causative agent of the winter vomiting disease and the leading cause of outbreaks of gastrointestinal infections across all settings and age groups in the world. The virus is highly contagious making outbreaks difficult or often impossible to control and having a high impact on societal costs and resources. LÄS MER

  5. 4. Processing and presentation of exogenous antigen by dendritic cells

    Författare :Liying Chen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :DC; vesicular MHC-I processing; Adenosine; CD 1 d; TACA;

    Sammanfattning : Dendritic cells (DC) play a key role in the immune system. In this thesis, we have investigated and characterized pathways for the processing and presentation of exogenous OVA on MHC-I ("cross-presentation") and how these were influenced by the purine nucleoside Adenosine (Ado), an immune regulator that accumulates to high concentrations at sites of inflammation and tumor growth. LÄS MER

  7. 5. Studies of Carbohydrate-Binding Proteins from Enterotoxigenic Escherichia coli

    Författare :Lena Jansson; Göteborgs universitet; []
    Nyckelord :Carbohydrate recognition; ETEC colonization factors; CFA I fimbriae; CS6 protein; heat-labile enterotoxin;

    Sammanfattning : Knowledge about the carbohydrate binding specificity of pathogens can give an increased understanding of their virulence strategies, and is also of importance for the development of anti-adhesive therapies and vaccines. Enterotoxigenic Escherichia coli (ETEC) is a well-known causative agent of diarrheal disease. LÄS MER