Sökning: "gamma spectrometry"

Visar resultat 11 - 15 av 31 avhandlingar innehållade orden gamma spectrometry.

  1. 11. Development and Application of Software Tools for Mass Spectrometry Imaging

    Författare :Patrik Källback; Per E. Andrén; Per Svenningsson; Anna Nilsson; Benjamin Bowen; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; mass spectrometry imaging; MALDI; DESI; msIQuant; quantitation; neurotransmitters; drugs; derivatization; brain; compression; data entropy reduction;

    Sammanfattning : Mass spectrometry imaging (MSI) has been extensively used to produce qualitative maps of distributions of proteins, peptides, lipids, neurotransmitters, small molecule pharmaceuticals and their metabolites directly in biological tissue sections. Moreover, during the last 10 years, there has been growing demand to quantify target compounds in tissue sections of various organs. LÄS MER

  3. 12. Methods for localizing and quantifying radionuclide sources and deposition using in situ gamma spectrometry : Critical review of the peak-to-valley method based on experimental studies and applications in Georgia and Japan

    Författare :Karl Östlund; Malmö Medicinsk strålningsfysik; []
    Nyckelord :In situ gamma spectrometry;

    Sammanfattning : This thesis describes investigations made on mobile and stationary gammaspectrometry made both under laboratory conditions and in situ. The objective hasbeen to identify and quantify radionuclides in the form of point sources,contamination and widespread deposition in situations where the measurementgeometry is not known beforehand. LÄS MER

  4. 13. Targeted Abeta proteomics - A tool to study the pathogenesis of Alzheimer’s disease

    Författare :Erik Portelius; Göteborgs universitet; []
    Nyckelord :Alzheimer’s disease; Cerebrospinal fluid; Immunoprecipitation; Mass spectrometry; beta-amyloid;

    Sammanfattning : Alzheimer’s disease (AD) is an age-related progressive neurodegenerative disorder of the central nervous system. Diagnosis and monitoring of sporadic AD has long depended on clinical examination of individuals with end-stage disease. LÄS MER

  5. 14. Electropermeabilization in Experimental Tumour Treatment: Dosimetry and Tissue Effects

    Författare :Per Engström; Lund Medicinsk strålningsfysik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; liver; electroporation; ischemia; Electropermeabilization; ECT; Tumor; 111-In-BLMC; 99m-Tc-DTPA; glioma; rat; electric pulses; Impedance spectrometry; treatment; Physics; Fysik;

    Sammanfattning : Short, electric high-voltage pulses can be used to transiently increase the permeability of cell membranes without significant loss of cell viability. During this period of time, extracellular and normally non-permeant, molecules are accessed the cytoplasm and the cell nucleus. LÄS MER

  7. 15. Identification and investigation of gamma-secretase associated proteins from brain

    Författare :Yasuhiro Teranishi; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer disease (AD) is a progressive neurodegenerative disorder and the most common cause of dementia. The pathological hallmarks in the AD brain are extracellular deposition of amyloid plaques, mainly composed of the amyloid β-peptide (Aβ), and intracellular neurofibrillary tangles made of hyperphosphorylated tau. LÄS MER