Sökning: "functional somatic syndrome"
Visar resultat 1 - 5 av 16 avhandlingar innehållade orden functional somatic syndrome.
1. Functional gastrointestinal disorders : co-morbidity and non-somatic aspects
Sammanfattning : Aims of the thesis: The first aim, (Study I) of this thesis was to compare co-morbidity of the reported symptoms and its relation to healthcare seeking behaviour among non-patients who had persistent functional gastro-intestinal disorders (FGID) or who were strictly GI symptom free (SSF). The second aim (study II) was to compare FGID sufferers primary health care consumption, as registered in their medical records. LÄS MER
2. Genetic epidemiological studies of the functional somatic syndromes : chronic widespread pain and chronic fatigue
Sammanfattning : Fibromyalgia and chronic fatigue syndrome are two symptom-defined conditions with many physical symptoms in common, such as muscle pain, fatigue, unrefreshing sleep, and impairment in memory or concentration. These two conditions often co-occur and frequently co-exist with other symptom-defined conditions (e.g. LÄS MER
3. Irritable bowel syndrome - a disorder of gut-brain interaction
Sammanfattning : Irritable bowel syndrome (IBS) is a common and multifactorial functional gastrointestinal (GI) disorder characterized by altered gut-brain communication. Due to the complexity of gut-brain interactions, the aim of this thesis was to enhance the understanding of associations between GI symptom severity and measures from multiple levels along the gut-brain axis in IBS patients. LÄS MER
4. Peripheral and Central Mechanisms in Irritable Bowel Syndrome : in search of links
Sammanfattning : Irritable bowel syndrome (IBS) is a chronic visceral pain disorder with female predominance, characterized by recurrent abdominal pain and disturbed bowel habits in the absence of an identifiable organic cause. This prevalent and debilitating disease, which accounts for a substantial economic and individual burden, lacks exact diagnostic tools and effective treatment, since its pathophysiology remains uncertain. LÄS MER
5. Role of DNA repair in class switch recombination and somatic hypermutation
Sammanfattning : Class switch recombination (CSR) and somatic hypermutation (SHM), occurring in the germinal center, are two important processes for B cell development. Both are initiated by activation-induced cytidine deaminase (AID), through deamination of the C residues in the variable and switch regions of the immunoglobulin locus, resulting in either in single stranded or double stranded DNA breaks. LÄS MER