Sökning: "fibre morphology"

Visar resultat 16 - 20 av 63 avhandlingar innehållade orden fibre morphology.

1. 16. Cytotoxic Cyclotides : Structure, Activity, and Mode of Action

   Författare :Erika Svangård; Per Claeson; Lars Bohlin; Ulf Göransson; John H. Cardellina II; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmacognosy; cyclotide; cytotoxic; cancer; cyclic cystine knot; Viola; Violaceae; liposome; hollow fibre; homology modelling; mass spectrometry; amphipathic; structure–activity; tumour; membrane disruption; necrosis; Farmakognosi; Pharmacognosy; Farmakognosi;

   Sammanfattning : Cyclotides are small cyclic plant proteins, and this thesis addresses their cytotoxic structure-activity properties and their mode of action on human cancer cell lines. Cyclotides were isolated from Viola odorata and Viola tricolor; three novel cyclotide sequences and two known sequences, but of new origin, were identified using mass spectrometry, amino acid analysis, and Edman degradation. LÄS MER

3. 17. Chronic anterior cruciate ligament tear : knee function and knee extensor muscle size, morphology and function before and after surgical reconstruction

   Författare :Lars-Gunnar Elmqvist; Umeå universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; knee joint; ligaments; articular; surgery; muscle fibre; isokinetics; exercise therapy; muscular atrophy; electromyography;

   Sammanfattning : Knee function was evaluated by knee score, activity level, clinical findings and performance tests, muscle size by computerized tomography (CT), morphology by light (LM) and electron microscopy (EM), muscle function by electromyography (EMG) and isokinetic performance in 29 patients with chronic anterior cruciate ligament (ACL) tear. Preoperatively CT disclosed a significant mean atrophy of the quadriceps and nonsignificant changes of the other muscle areas of the injured leg. LÄS MER

4. 18. Ocular function and morphology in humans and rabbits exposed to vigabatrin medication

   Författare :Ulrika Kjellström; Lund Oftalmologi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vimentin; PKC-alpha; visual field defects; optical coherence tomography; full-field electroretinography; GABA; vigabatrin;

   Sammanfattning : Vigabatrin is an antiepileptic drug that is known to cause visual field defects and retinal dysfunction measured by full-field electroretinography (ff-ERG). Underlying mechanisms have not yet been elucidated. LÄS MER

5. 19. Craniofacial morphology and growth in the ferret: effects from alteration of masticatory function

   Författare :Tailun He; Göteborgs universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

   Sammanfattning : INTRODUCTION: Our hypothesis is that any effects on craniofacial growth and morphology induced by altering the masticatory function will vary according to the species involved. The general aim of this thesis was to test the possible effects of altering the masticatory function on craniofacial growth and morphology, as well as features of masticatory muscles in ferrets. LÄS MER

7. 20. Determination of Weibull Parameters by Single Fibre Fragmentation for use in Modelling of Paper Tensile Properties

   Författare :Carl-Henrik Ljungqvist; []
   Nyckelord :;

   Sammanfattning : The thesis presents a method for characterization of pulp fibre tensile strength. Single Fibre Fragmentation (SFF) and Weibull statistics were used. Methods for specimen preparation, sampling and analysis of fragmentation data from digital images were developed. LÄS MER