Sökning: "PKC-alpha"

Hittade 4 avhandlingar innehållade ordet PKC-alpha.

  1. 1. Ocular function and morphology in humans and rabbits exposed to vigabatrin medication

    Författare :Ulrika Kjellström; Lund Oftalmologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vimentin; PKC-alpha; visual field defects; optical coherence tomography; full-field electroretinography; GABA; vigabatrin;

    Sammanfattning : Vigabatrin is an antiepileptic drug that is known to cause visual field defects and retinal dysfunction measured by full-field electroretinography (ff-ERG). Underlying mechanisms have not yet been elucidated. LÄS MER

  3. 2. Leishmania donovani Lipophosphoglycan : Modulation of Macrophage and Dendritic Cell Function

    Författare :Katarina Tejle; Birgitta Rasmusson; Karl-Eric Magnusson; Olle Stendahl; Marita Troye-Blomberg; Linköpings universitet; []
    Nyckelord :LANTBRUKSVETENSKAPER; AGRICULTURAL SCIENCES; Lipophosphoglycan; Leishmania donovani; macrophage; actin; phagocytosis; PKC alpha; dendritic cell; Microbiology and immunology; Mikrobiologi och immunologi;

    Sammanfattning : Leishmania donovani is a blood-borne tropicial parasite, which infects humans through bites by Phlebotomus sandflies. The parasite survives and multiplies inside macrophages in inner organs, and causes the deadly disease visceral leishmaniasis (Kala-Azar). LÄS MER

  4. 3. The expression and function of protein kinase C isoforms in differentiating neuroblastoma cells

    Författare :Sofia Fagerström; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Neurologi; neurophysiology; neuropsychology; Neurology; p130cas; PKC; fte-1; neuroblastoma; SH-SY5Y cells; growth cones; neuronal differentiation; neuropsykologi; neurofysiologi;

    Sammanfattning : The human neuroblastoma cell line SH-SY5Y can be induced to differentiate into a neuronal sympathetic phenotype after treatment with 16 nM 12-O-tetradecanoyl phorbol 13-acetate (TPA) in serum, or by a combination of the growth factors basic fibroblast growth factor and insulin-like growth factor-I (bFGF/IGF-I). SH-SY5Y cells stably transfected with TrkA, the nerve growth factor (NGF) receptor, differentiate in response to NGF. LÄS MER

  5. 4. Apolipoprotein E and Alzheimer's diseases : signals and effects

    Författare :Ángel Cedazo-Minguez; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Alzheimer's Disease (AD) is the most frequent cause of dementia in the elderly. A diagnosis of AD is confirmed post-mortem by the accumulation of neuritic plaques (NP) and neurofibrillary tangles (NFTs) in brain tissue. LÄS MER