Sökning: "evolutionary machine learning"
Visar resultat 1 - 5 av 19 avhandlingar innehållade orden evolutionary machine learning.
1. Evolving intelligence : Overcoming challenges for Evolutionary Deep Learning
Sammanfattning : Deep Learning (DL) has achieved remarkable results in both academic and industrial fields over the last few years. However, DL models are often hard to design and require proper selection of features and tuning of hyper-parameters to achieve high performance. These selections are tedious for human experts and require substantial time and resources. LÄS MER
2. Advancing systems biology of yeast through machine learning and comparative genomics
Sammanfattning : Synthetic biology has played a pivotal role in accomplishing the production of high value commodities, pharmaceuticals, and bulk chemicals. Fueled by the breakthrough of synthetic biology and metabolic engineering, Saccharomyces cerevisiae and various other yeasts (such as Yarrowia lipolytica , Pichia pastoris ) have been proven to be promising microbial cell factories and are frequently used in scientific studies. LÄS MER
3. Advancing Evolutionary Biology: Genomics, Bayesian Statistics, and Machine Learning
Sammanfattning : During the recent decades the field of evolutionary biology has entered the era of big data, which has transformed the field into an increasingly computational discipline. In this thesis I present novel computational method developments, including their application in empirical case studies. LÄS MER
4. Combining Evolution and Physics through Machine Learning to Decipher Molecular Mechanisms
Sammanfattning : From E.coli to elephants, the cells of all living organisms are surrounded by a near impenetrable wall of lipids. The windows through the walls are membrane proteins - receptors, transporters and channels that confer communication, information and metabolites through the membrane. LÄS MER
5. Mapping the proteome with data-driven methods: A cycle of measurement, modeling, hypothesis generation, and engineering
Sammanfattning : The living cell exhibits emergence of complex behavior and its modeling requires a systemic, integrative approach if we are to thoroughly understand and harness it. The work in this thesis has had the more narrow aim of quantitatively characterizing and mapping the proteome using data-driven methods, as proteins perform most functional and structural roles within the cell. LÄS MER