Avancerad sökning

Visar resultat 1 - 5 av 19 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Studies of α-D-isosaccharinic Acid – Acid dissociation constant and structural conformations

   Författare :Stefan Ekberg; Chalmers tekniska högskola; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; α-D-isosaccharinate; nuclear repository; α-D-isosaccharinic acid; potentiometric titration; equilibrium; acid dissociation constant; nuclear waste; stability constant; ion chromatography; α-D-isosaccharino-1; 4-lactone;

   Sammanfattning : .... LÄS MER

3. 2. Antivirulent and antibiofilm salicylidene acylhydrazide complexes in solution and at interfaces

   Författare :Shoghik Hakobyan; Madeleine Ramstedt; Jean-Francois Boily; Mikael Elofsson; Marcus Textor; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antivirulent; Antibiofilm; Hydrazones; Gallium; Pseudomonas aeruginosa; Type three secretion system; Equilibrium constant; Chemical equilibrium modelling; Spectrophotometric titration; UV-Vis;

   Sammanfattning : The growing bacterial resistance against antibiotics creates a limitation for using traditional antibiotics and requests development of new approaches for treatment of bacterial infections. Among the bacterial infections that are most difficult to treat, biofilm-associated infections are one of the most hazardous. LÄS MER

4. 3. Gas-Phase Protein Structure Under the Computational Microscope : Hydration, Titration, and Temperature

   Författare :Erik Marklund; David van der Spoel; Albert Heck; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Molecular dynamics; gas phase; proteins; micelles; proton transfer; Grothuss mechanism; kinetics; Physics; Fysik; Physics with specialization in Biophysics; Fysik med inriktning mot biofysik;

   Sammanfattning : Although the native environment of the vast majority of proteins is a complex aqueous solution, like the interior of a cell, many analysis methods for assessing chemical and physical properties of biomolecules require the sample to be aerosolized; that is, transferred to the gas-phase. An important example is electrospray-ionization mass spectrometry, which can provide a wide range of information about e. LÄS MER

5. 4. Statistical Mechanical Studies of Aqueous solutions and Biomolecular Systems

   Författare :Fernando Luis Barroso Da Silva; Beräkningskemi; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; highly charged macromolecules; dielectric discontinuity; dissociation constant; Tanford-Kirkwood model; protein mutation; electrostatic interactions; chemical potential; titration; biomolecules; computer simulations; radial distribution function; electrolyte solutions; continuum model.; Theoretical chemistry; quantum chemistry; Teoretisk kemi; kvantkemi;

   Sammanfattning : This thesis is concerned with theoretical studies of aqueous solutions and biomolecular systems. Part of the present work is to understand equilibrium solvent and solute properties, while the other part is to study processes that occur in these solutions. LÄS MER

7. 5. Protein folding studies of human superoxide dismutase and ALS associated mutants

   Författare :Mikael Lindberg; Mikael Oliveberg; Jane Clarke; Umeå universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; superoxide dismutase; ALS; protein folding; equilibrium titration; protein stability; apo protein; disulphide bridge; chevron plot; Biokemi; Biochemistry; Biokemi; Biochemistry; biokemi;

   Sammanfattning : Proteins are among the most abundant biological macromolecules. The cellular machinery is coupled to exact structural shape and properties of the more than 100 000 different proteins. Still, proteins can sometimes completely change their character and as a result trigger neuro degenerative disease. LÄS MER