Sökning: "Marcus Textor"

Hittade 3 avhandlingar innehållade orden Marcus Textor.

  1. 1. Antivirulent and antibiofilm salicylidene acylhydrazide complexes in solution and at interfaces

    Författare :Shoghik Hakobyan; Madeleine Ramstedt; Jean-Francois Boily; Mikael Elofsson; Marcus Textor; Umeå universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Antivirulent; Antibiofilm; Hydrazones; Gallium; Pseudomonas aeruginosa; Type three secretion system; Equilibrium constant; Chemical equilibrium modelling; Spectrophotometric titration; UV-Vis;

    Sammanfattning : The growing bacterial resistance against antibiotics creates a limitation for using traditional antibiotics and requests development of new approaches for treatment of bacterial infections. Among the bacterial infections that are most difficult to treat, biofilm-associated infections are one of the most hazardous. LÄS MER

  3. 2. Spatially Controlled Covalent Immobilization of Biomolecules on Silicon Surfaces

    Författare :Elisabeth Pavlovic; Sven Oscarsson; Marcus Textor; Uppsala universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Biotechnology; silicon oxide; electrooxidation; sulfur; nanotechnology; self-assembled monolayers; atomic force microscopy; electron spectroscopy for chemical analysis; biomolecules; covalent immobilization; reversibility; Bioteknik; Bioengineering; Bioteknik;

    Sammanfattning : The work described in this thesis aims to achieving surface patterning through chemical activation of thiolated silicon oxide surfaces, resulting in a spatially controlled covalent immobilization of biomolecules with high resolution.Existing chemical methods to immobilize molecules on surfaces do not reach below the micrometer scale while the ones allowing for spatial control mostly lead to non-covalent adsorption of molecules on surfaces, or require several successive chemical reactions to obtain the final covalent immobilization. LÄS MER

  4. 3. Environment-Sensitive Multifunctional Drug Delivery Systems

    Författare :Jian Qin; Mamoun Muhammed; Marcus Textor; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Materials chemistry; Materialkemi;

    Sammanfattning : Drug delivery systems (DDS) with multiple functionalities such as environment-sensitive drug release mechanisms and visualization agents have motivated the biomedical community as well as materials chemists for more than a decade. This dissertation is concerned with the development of nanoparticles for multifunctional DDS  to tackle several crucial challenges in these complex systems, including polymeric nanospheres which respond to temperature change, superparamagnetic iron oxide nanoparticles/polymeric composite for magnetic resonance imaging contrast agents and drug carriers, immunoresponse of nanomaterials and injectable magnetic field sensitive ferrogels. LÄS MER