Sökning: "endothelial dysfunction and left ventricular dysfunction"

Visar resultat 6 - 10 av 14 avhandlingar innehållade orden endothelial dysfunction and left ventricular dysfunction.

  1. 6. Gene environment-interaction and cardiovascular phenotype in obesity and diabetes

    Författare :Shafaat Hussain; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Although a large body of evidence supports the notion that genes determine cardio-metabolic traits and outcomes, the non-genetic regulation of these events has recently gained increasing attention. Plastic chemical modifications of DNA-histone complexes defined epigenetic changes regulate gene expression by modifying chromatin accessibility to transcription factors. LÄS MER

  3. 7. Primary Hyperparathyroidism : A Study of Cardiovascular Dysfunction and its Reversibility After Parathyroidectomy

    Författare :Inga-Lena Nilsson; Lars-Ove Farnebo; Uppsala universitet; []
    Nyckelord :Medical sciences; primary hyperparathyroidism; vascular endothelium; heart; heart rate variability; blood pressure; parathyroidectomy; calcium; parathyroid hormone; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Surgery; kirurgi;

    Sammanfattning : Cardiovascular risk in primary hyperparathyroidism (HPT) is controversial, and studies mainly from Europe associate HPT with increased cardiovascular morbidity and mortality. Cardiovascular morphology and function were evaluated prospectively in 31 consecutive HPT patients (mean serum calcium 2.97±0. LÄS MER

  4. 8. Studies on incretins and cardiovascular function

    Författare :David Nathanson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Type 2 diabetes (T2DM) is a strong risk factor for coronary heart disease (CHD). A great many diabetic subjects suffer from congestive heart failure (CHF), a condition with a high concomitant mortality. So far, attempts aimed at reducing macrovascular complications in T2DM have been essentially futile. LÄS MER

  5. 9. Cardiovascular health in children and adolescents with obesity : prevalence, prediction and supervised exercise

    Författare :Pernilla Hedvall Kallerman; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Background: Cardiovascular disease (CVD) is a major cause of death worldwide and is preceded by a long process in which several cardiovascular (CV) risk factors are present, sometimes already in childhood. Some of these risk factors such as non-dipping blood pressure and microvascular endothelial dysfunction and possible associated factors are little studied among children with obesity. LÄS MER

  7. 10. The interplay between the endocrine and cardiovascular systems. A study of the hormonal influence on cardiovascular function and endothelial nitric oxide synthase (eNOS) expression

    Författare :Anna Wickman; Göteborgs universitet; []
    Nyckelord :hypophysectomy · growth hormone · insulin-like growth factor-I · estrogen · vascular reactivity · endothelial function · endothelial nitric oxide synthase · nitric oxide · cardiovascular function · vasculature · kidney · hypertension;

    Sammanfattning : During the present thesis, special interest was focused on the cardiovascular effects of growth hormone (GH) and estrogen (E2) and combined treatment of GH+E2, in particular the possible effects on endothelial nitric oxide synthase (eNOS) expression and nitric oxide (NO) bioavailability for maintaining cardiovascular homeostasis. The possible role of fluid mechanical force e. LÄS MER