Sökning: "endocrine tumour"

Visar resultat 21 - 25 av 36 avhandlingar innehållade orden endocrine tumour.

  1. 21. Galanin in the pituitary and in human circulation : clinical and experimental studies

    Författare :Eva Grenbäck; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The neuropeptide galanin has important roles in the central and peripheral nervous systems where it affects memory, seizure activity, appetite and pain transmission. Galanin is also present in the endocrine system and one of its most prominent effects is to stimulate the release of growth hormone (GH). LÄS MER

  3. 22. TISSUE MICROARRAY PERSPECTIVES ON CYCLIN D1 IN BREAST CANCER: Progression, prognosis and prediction

    Författare :Karin Jirström; Tumörmikromiljö; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pathological anatomy; General pathology; tamoxifen resistance; CCND1; Breast cancer; tissue microarrays; Patologi allmän ; patologisk anatomi;

    Sammanfattning : Breast cancer is a truly heterogenous disease, reflected in the existence of a wide spectrum of phenotypic subsets of tumours with varying intrinsic aggressiveness as well as ability to respond to a given treatment. Recent advances in large-scale genomic and proteomic screening techniques have confirmed this heterogeneity also at a molecular level, but there is still a bottleneck to be overcome before the discoveries in the laboratory can be translated into the much more complex clinical situation in order to develop better targeted therapies. LÄS MER

  4. 23. Estrogen receptor β signalling in mammary epithelial and breast cancer cells

    Författare :Karolina Lindberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Estrogens are key players in the etiology and progression of breast cancer, and mediate their effects through the estrogen receptors (ERα and ERβ). ERα plays important roles in proliferation and progression of breast cancer, whereas a distinct function of ERβ in the initiation and development of breast cancer is not yet clearly established. LÄS MER

  5. 24. The rehabilitation process after breast cancer diagnosis : factors of importance for return to work

    Författare :Aina Johnsson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The most common female cancer in Western countries is breast cancer and women diagnosed with this disease are often under 65 years old. With increasing prevalence of survivors it is important to shed light on problems facing these women after diagnosis and treatment. LÄS MER

  7. 25. Clinical potential of the mTOR effectors S6K1, S6K2 and 4EBP1 in breast cancer

    Författare :Elin Karlsson; Olle Stål; Anna-Lotta Hallbeck; Patrik Lundström; Catharina Larsson; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : The prognosis of patients diagnosed with breast cancer has been considerably improved in the latest 25 years, as a result of continuous development of diagnostics and treatment regimens. Though, tumour diseases, for woman mainly lung cancer and breast cancer, still constitute of the most common causes of death in developed countries, following heart diseases. LÄS MER